NUEVOS DERIVADOS DE 6-FENILDIHIDROPIRROLPIRIMIDINDIONA
Nuevos derivados de 6-fenildihidropirrolpirimidindiona y sales farmacéuticamente aceptables de los mismos,**fórmula** en donde R1 R2, R3, R4 y R5 son restos orgánicos, L1 es un grupo de enlace y R6 es -C(O) NR10R11, -S(O)2NR10R11, -ON=CR12R13, o un grupo heterociclilo, arilo o heteroarilo, donde R10...
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| creator | VIDAL JUAN BERNAT SEGARRA MATAMOROS VICTOR FERNANDEZ GONZALEZ FRANCO LOZA GARCIA MARIA ISABEL RAVINA RUBIRA ENRIQUE ESTEVE TRIAS CRISTINA |
| description | Nuevos derivados de 6-fenildihidropirrolpirimidindiona y sales farmacéuticamente aceptables de los mismos,**fórmula** en donde R1 R2, R3, R4 y R5 son restos orgánicos, L1 es un grupo de enlace y R6 es -C(O) NR10R11, -S(O)2NR10R11, -ON=CR12R13, o un grupo heterociclilo, arilo o heteroarilo, donde R10, R11, R12 y R13 son restos orgánicos, que tienen potencial terapéutico como inhibidores de receptor de adenosina A2.
6-phenylpyrrolopyrimidinedione derivatives of the formula (I), and pharmaceutically acceptable salts thereof, wherein R , R , R , R and R are organic residues, L1 is a spacer group and R is C(O) NR R , -S(O)2NR R , ?-ON=CR R , or a heterocyclyl, aryl? or heteroaryl group, where R , R , R and R are organic residues, have therapeutic potential as A2 adenosine receptor inhibitors. |
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6-phenylpyrrolopyrimidinedione derivatives of the formula (I), and pharmaceutically acceptable salts thereof, wherein R , R , R , R and R are organic residues, L1 is a spacer group and R is C(O) NR R , -S(O)2NR R , ?<custom-character file="US20050070558A1-20050331-P00900.TIF" wi="20" he="20" id="custom-character-00001"/>-ON=CR R , or a heterocyclyl, aryl?<custom-character file="US20050070558A1-20050331-P00900.TIF" wi="20" he="20" id="custom-character-00002"/> or heteroaryl group, where R , R , R and R are organic residues, have therapeutic potential as A2 adenosine receptor inhibitors.</description><edition>7</edition><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050216&DB=EPODOC&CC=ES&NR=2193839B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050216&DB=EPODOC&CC=ES&NR=2193839B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VIDAL JUAN BERNAT</creatorcontrib><creatorcontrib>SEGARRA MATAMOROS VICTOR</creatorcontrib><creatorcontrib>FERNANDEZ GONZALEZ FRANCO</creatorcontrib><creatorcontrib>LOZA GARCIA MARIA ISABEL</creatorcontrib><creatorcontrib>RAVINA RUBIRA ENRIQUE</creatorcontrib><creatorcontrib>ESTEVE TRIAS CRISTINA</creatorcontrib><title>NUEVOS DERIVADOS DE 6-FENILDIHIDROPIRROLPIRIMIDINDIONA</title><description>Nuevos derivados de 6-fenildihidropirrolpirimidindiona y sales farmacéuticamente aceptables de los mismos,**fórmula** en donde R1 R2, R3, R4 y R5 son restos orgánicos, L1 es un grupo de enlace y R6 es -C(O) NR10R11, -S(O)2NR10R11, -ON=CR12R13, o un grupo heterociclilo, arilo o heteroarilo, donde R10, R11, R12 y R13 son restos orgánicos, que tienen potencial terapéutico como inhibidores de receptor de adenosina A2.
6-phenylpyrrolopyrimidinedione derivatives of the formula (I), and pharmaceutically acceptable salts thereof, wherein R , R , R , R and R are organic residues, L1 is a spacer group and R is C(O) NR R , -S(O)2NR R , ?<custom-character file="US20050070558A1-20050331-P00900.TIF" wi="20" he="20" id="custom-character-00001"/>-ON=CR R , or a heterocyclyl, aryl?<custom-character file="US20050070558A1-20050331-P00900.TIF" wi="20" he="20" id="custom-character-00002"/> or heteroaryl group, where R , R , R and R are organic residues, have therapeutic potential as A2 adenosine receptor inhibitors.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDDzC3UN8w9WcHEN8gxzdAGzFMx03Vz9PH1cPD08XYL8AzyDgvx9gKSnr6eLp5-Lp7-fIw8Da1piTnEqL5TmZlBwcw1x9tBNLciPTy0uSExOzUstiXcNNjK0NLYwtnQyNCZCCQDtGyf5</recordid><startdate>20050216</startdate><enddate>20050216</enddate><creator>VIDAL JUAN BERNAT</creator><creator>SEGARRA MATAMOROS VICTOR</creator><creator>FERNANDEZ GONZALEZ FRANCO</creator><creator>LOZA GARCIA MARIA ISABEL</creator><creator>RAVINA RUBIRA ENRIQUE</creator><creator>ESTEVE TRIAS CRISTINA</creator><scope>EVB</scope></search><sort><creationdate>20050216</creationdate><title>NUEVOS DERIVADOS DE 6-FENILDIHIDROPIRROLPIRIMIDINDIONA</title><author>VIDAL JUAN BERNAT ; SEGARRA MATAMOROS VICTOR ; FERNANDEZ GONZALEZ FRANCO ; LOZA GARCIA MARIA ISABEL ; RAVINA RUBIRA ENRIQUE ; ESTEVE TRIAS CRISTINA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2193839B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2005</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>VIDAL JUAN BERNAT</creatorcontrib><creatorcontrib>SEGARRA MATAMOROS VICTOR</creatorcontrib><creatorcontrib>FERNANDEZ GONZALEZ FRANCO</creatorcontrib><creatorcontrib>LOZA GARCIA MARIA ISABEL</creatorcontrib><creatorcontrib>RAVINA RUBIRA ENRIQUE</creatorcontrib><creatorcontrib>ESTEVE TRIAS CRISTINA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>VIDAL JUAN BERNAT</au><au>SEGARRA MATAMOROS VICTOR</au><au>FERNANDEZ GONZALEZ FRANCO</au><au>LOZA GARCIA MARIA ISABEL</au><au>RAVINA RUBIRA ENRIQUE</au><au>ESTEVE TRIAS CRISTINA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NUEVOS DERIVADOS DE 6-FENILDIHIDROPIRROLPIRIMIDINDIONA</title><date>2005-02-16</date><risdate>2005</risdate><abstract>Nuevos derivados de 6-fenildihidropirrolpirimidindiona y sales farmacéuticamente aceptables de los mismos,**fórmula** en donde R1 R2, R3, R4 y R5 son restos orgánicos, L1 es un grupo de enlace y R6 es -C(O) NR10R11, -S(O)2NR10R11, -ON=CR12R13, o un grupo heterociclilo, arilo o heteroarilo, donde R10, R11, R12 y R13 son restos orgánicos, que tienen potencial terapéutico como inhibidores de receptor de adenosina A2.
6-phenylpyrrolopyrimidinedione derivatives of the formula (I), and pharmaceutically acceptable salts thereof, wherein R , R , R , R and R are organic residues, L1 is a spacer group and R is C(O) NR R , -S(O)2NR R , ?<custom-character file="US20050070558A1-20050331-P00900.TIF" wi="20" he="20" id="custom-character-00001"/>-ON=CR R , or a heterocyclyl, aryl?<custom-character file="US20050070558A1-20050331-P00900.TIF" wi="20" he="20" id="custom-character-00002"/> or heteroaryl group, where R , R , R and R are organic residues, have therapeutic potential as A2 adenosine receptor inhibitors.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NUEVOS DERIVADOS DE 6-FENILDIHIDROPIRROLPIRIMIDINDIONA |
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