FENIL-DIHIDROBENZOFURANOS

LOS COMPUESTOS DE FORMULA (I), DONDE R1, R2, R3 Y R4 Y R5 TIENEN LOS SIGNIFICADOS CITADOS EN LA MEMORIA DESCRIPTIVA, SON AGENTES NUEVOS Y POTENTES INHIBIDORES DE LA PDE. PCT No. PCT/EP96/02031 Sec. 371 Date Nov. 18, 1997 Sec. 102(e) Date Nov. 18, 1997 PCT Filed May 11, 1996 PCT Pub. No. WO96/36625 P...

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Hauptverfasser: BAR, THOMAS, MARTIN, THOMAS, THIBAUT, ULRICH, AMSCHLER, HERMANN, GUTTERER, BEATE, FLOCKERZI, DIETER
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creator BAR, THOMAS
MARTIN, THOMAS
THIBAUT, ULRICH
AMSCHLER, HERMANN
GUTTERER, BEATE
FLOCKERZI, DIETER
description LOS COMPUESTOS DE FORMULA (I), DONDE R1, R2, R3 Y R4 Y R5 TIENEN LOS SIGNIFICADOS CITADOS EN LA MEMORIA DESCRIPTIVA, SON AGENTES NUEVOS Y POTENTES INHIBIDORES DE LA PDE. PCT No. PCT/EP96/02031 Sec. 371 Date Nov. 18, 1997 Sec. 102(e) Date Nov. 18, 1997 PCT Filed May 11, 1996 PCT Pub. No. WO96/36625 PCT Pub. Date Nov. 21, 1996Compounds of formula I are selective cyclic nucleotide phosphodiesterase (PDE) inhibitors (namely of type IV). They and pharmaceutical compositions in which they are active ingredients are useful as bronchial therapeutics, for elimination of erectile dysfunction and for treatment of disorders, particularly those of inflammatory nature. The compounds are distinguished by low toxicity, good enteral absorption (high bioavailability), a great therapeutic breadth and the absence of significant side effects.
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PCT No. PCT/EP96/02031 Sec. 371 Date Nov. 18, 1997 Sec. 102(e) Date Nov. 18, 1997 PCT Filed May 11, 1996 PCT Pub. No. WO96/36625 PCT Pub. Date Nov. 21, 1996Compounds of formula I are selective cyclic nucleotide phosphodiesterase (PDE) inhibitors (namely of type IV). They and pharmaceutical compositions in which they are active ingredients are useful as bronchial therapeutics, for elimination of erectile dysfunction and for treatment of disorders, particularly those of inflammatory nature. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FENIL-DIHIDROBENZOFURANOS
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