DERIVADOS DE AZAINDOL ETILAMINA COMO AGENTES DE UNION AL RECEPTOR NICOTINICO DE ACETILCOLINA

LOS COMPUESTOS CON LA FORMULA I SON UTILES EN EL TRATAMIENTO DE LAS CONDICIONES ASOCIADAS A LA DISMINUCION DE LOS RECEPTORES NICOTINICOS EN LOS MAMIFEROS. EN LA QUE X CORRESPONDE A: A) CH 2 NR 1 R 2 B) O C) Y R, R 1 Y R 2 CORRESPONDEN INDEPENDIENTEMENTE A UN HIDROGENO Y UN ALQUILO C SUB,1 C 6 ; R 3...

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description LOS COMPUESTOS CON LA FORMULA I SON UTILES EN EL TRATAMIENTO DE LAS CONDICIONES ASOCIADAS A LA DISMINUCION DE LOS RECEPTORES NICOTINICOS EN LOS MAMIFEROS. EN LA QUE X CORRESPONDE A: A) CH 2 NR 1 R 2 B) O C) Y R, R 1 Y R 2 CORRESPONDEN INDEPENDIENTEMENTE A UN HIDROGENO Y UN ALQUILO C SUB,1 C 6 ; R 3 SE SELECCIONA ENTRE UN HIDROGENO, UN HALOGENO Y UN ALQUILO C 1 C 6 ; I EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4; M EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4, Y N EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 2; O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS. Compounds of formula I are useful in treatment of conditions associated with depletion of nicotine receptors in mammals. wherein X is: a) -CH2NR R , b) or; c) and R,R and R are independently selected from hydrogen and C1-C6 alkyl; R is selected from hydrogen, halogen and C1-C6 alkyl; l is an integer from 0-4;m is an integer from 0-4; and n is an integer from 0-2; or a pharmaceutically acceptable salt thereof.
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EN LA QUE X CORRESPONDE A: A) CH 2 NR 1 R 2 B) O C) Y R, R 1 Y R 2 CORRESPONDEN INDEPENDIENTEMENTE A UN HIDROGENO Y UN ALQUILO C SUB,1 C 6 ; R 3 SE SELECCIONA ENTRE UN HIDROGENO, UN HALOGENO Y UN ALQUILO C 1 C 6 ; I EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4; M EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4, Y N EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 2; O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS. Compounds of formula I are useful in treatment of conditions associated with depletion of nicotine receptors in mammals. wherein X is: a) -CH2NR R , b) or; c) and R,R and R are independently selected from hydrogen and C1-C6 alkyl; R is selected from hydrogen, halogen and C1-C6 alkyl; l is an integer from 0-4;m is an integer from 0-4; and n is an integer from 0-2; or a pharmaceutically acceptable salt thereof.</description><edition>7</edition><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20021116&amp;DB=EPODOC&amp;CC=ES&amp;NR=2175615T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20021116&amp;DB=EPODOC&amp;CC=ES&amp;NR=2175615T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NAGEL, ARTHUR ADAM</creatorcontrib><title>DERIVADOS DE AZAINDOL ETILAMINA COMO AGENTES DE UNION AL RECEPTOR NICOTINICO DE ACETILCOLINA</title><description>LOS COMPUESTOS CON LA FORMULA I SON UTILES EN EL TRATAMIENTO DE LAS CONDICIONES ASOCIADAS A LA DISMINUCION DE LOS RECEPTORES NICOTINICOS EN LOS MAMIFEROS. EN LA QUE X CORRESPONDE A: A) CH 2 NR 1 R 2 B) O C) Y R, R 1 Y R 2 CORRESPONDEN INDEPENDIENTEMENTE A UN HIDROGENO Y UN ALQUILO C SUB,1 C 6 ; R 3 SE SELECCIONA ENTRE UN HIDROGENO, UN HALOGENO Y UN ALQUILO C 1 C 6 ; I EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4; M EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4, Y N EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 2; O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS. Compounds of formula I are useful in treatment of conditions associated with depletion of nicotine receptors in mammals. wherein X is: a) -CH2NR R , b) or; c) and R,R and R are independently selected from hydrogen and C1-C6 alkyl; R is selected from hydrogen, halogen and C1-C6 alkyl; l is an integer from 0-4;m is an integer from 0-4; and n is an integer from 0-2; or a pharmaceutically acceptable salt thereof.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQRbexEPUO4wEsYojWw-6oA5sZSUYLEUKQtRINxPujCR7A5r_mvT9110AVnzFoDYEAL8gSNAIZRyxZELyWCrgnMRqVk7AKYISKPB1NKxD2ajzseOGH1mv8xnM3ubePPi1-nLnljswfVql7Nanv2lt6pndD9TrbFpusMMvzf5wPiLcyYw</recordid><startdate>20021116</startdate><enddate>20021116</enddate><creator>NAGEL, ARTHUR ADAM</creator><scope>EVB</scope></search><sort><creationdate>20021116</creationdate><title>DERIVADOS DE AZAINDOL ETILAMINA COMO AGENTES DE UNION AL RECEPTOR NICOTINICO DE ACETILCOLINA</title><author>NAGEL, ARTHUR ADAM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2175615TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2002</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>NAGEL, ARTHUR ADAM</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NAGEL, ARTHUR ADAM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVADOS DE AZAINDOL ETILAMINA COMO AGENTES DE UNION AL RECEPTOR NICOTINICO DE ACETILCOLINA</title><date>2002-11-16</date><risdate>2002</risdate><abstract>LOS COMPUESTOS CON LA FORMULA I SON UTILES EN EL TRATAMIENTO DE LAS CONDICIONES ASOCIADAS A LA DISMINUCION DE LOS RECEPTORES NICOTINICOS EN LOS MAMIFEROS. EN LA QUE X CORRESPONDE A: A) CH 2 NR 1 R 2 B) O C) Y R, R 1 Y R 2 CORRESPONDEN INDEPENDIENTEMENTE A UN HIDROGENO Y UN ALQUILO C SUB,1 C 6 ; R 3 SE SELECCIONA ENTRE UN HIDROGENO, UN HALOGENO Y UN ALQUILO C 1 C 6 ; I EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4; M EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 4, Y N EQUIVALE A UN NUMERO ENTERO ENTRE 0 Y 2; O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS. Compounds of formula I are useful in treatment of conditions associated with depletion of nicotine receptors in mammals. wherein X is: a) -CH2NR R , b) or; c) and R,R and R are independently selected from hydrogen and C1-C6 alkyl; R is selected from hydrogen, halogen and C1-C6 alkyl; l is an integer from 0-4;m is an integer from 0-4; and n is an integer from 0-2; or a pharmaceutically acceptable salt thereof.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DERIVADOS DE AZAINDOL ETILAMINA COMO AGENTES DE UNION AL RECEPTOR NICOTINICO DE ACETILCOLINA
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