INHIBIDORES IRREVERSIBLES DE TIROSINA QUINASAS
LA PRESENTE INVENCION PROPORCIONA COMPUESTOS QUE SON INHIBIDORES IRREVERSIBLES DE LAS CINASAS DE LA TIROSINA. SE PROPORCIONA IGUALMENTE UN PROCEDIMIENTO PARA TRATAR EL CANCER, LA RESTENOSIS, LA ATEROSCLEROSIS, LA ENDOMETRIOSIS Y EL PSORIASIS, ASI COMO UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN CO...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | spa |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | DENNY, WILLIAM ALEXANDER DOHERTY, ANNETTE, MARIAN FRY, DAVID, W MCNAMARA, DENNIS, JOSEPH DOBRUSIN, ELLEN, MYRA BRIDGES, ALEXANDER, JAMES |
| description | LA PRESENTE INVENCION PROPORCIONA COMPUESTOS QUE SON INHIBIDORES IRREVERSIBLES DE LAS CINASAS DE LA TIROSINA. SE PROPORCIONA IGUALMENTE UN PROCEDIMIENTO PARA TRATAR EL CANCER, LA RESTENOSIS, LA ATEROSCLEROSIS, LA ENDOMETRIOSIS Y EL PSORIASIS, ASI COMO UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN COMPUESTO QUE ES INHIBIDOR IRREVERSIBLE DE LAS CINASAS DE LA TIROSINA.
The present invention relates to pyrimido [5,4-d] pyrimidine compounds of Formula II or a pharmaceutically acceptable salt thereof, wherein Q is and X, E1, E2, E3, R6 and p are as defined herein. The compounds of this invention are irreversible inhibitors of tyrosine kinases and are useful in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_ES2174250TT5</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ES2174250TT5</sourcerecordid><originalsourceid>FETCH-epo_espacenet_ES2174250TT53</originalsourceid><addsrcrecordid>eNrjZNDz9PPwdPJ08Q9yDVbwDApyDXMNCvZ08gHyXFwVQjyD_IM9_RwVAkOBZLBjMA8Da1piTnEqL5TmZlB0cw1x9tBNLciPTy0uSExOzUstiXcNNjI0NzEyNQgJMTUmRg0ACpkmbQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>INHIBIDORES IRREVERSIBLES DE TIROSINA QUINASAS</title><source>esp@cenet</source><creator>DENNY, WILLIAM ALEXANDER ; DOHERTY, ANNETTE, MARIAN ; FRY, DAVID, W ; MCNAMARA, DENNIS, JOSEPH ; DOBRUSIN, ELLEN, MYRA ; BRIDGES, ALEXANDER, JAMES</creator><creatorcontrib>DENNY, WILLIAM ALEXANDER ; DOHERTY, ANNETTE, MARIAN ; FRY, DAVID, W ; MCNAMARA, DENNIS, JOSEPH ; DOBRUSIN, ELLEN, MYRA ; BRIDGES, ALEXANDER, JAMES</creatorcontrib><description>LA PRESENTE INVENCION PROPORCIONA COMPUESTOS QUE SON INHIBIDORES IRREVERSIBLES DE LAS CINASAS DE LA TIROSINA. SE PROPORCIONA IGUALMENTE UN PROCEDIMIENTO PARA TRATAR EL CANCER, LA RESTENOSIS, LA ATEROSCLEROSIS, LA ENDOMETRIOSIS Y EL PSORIASIS, ASI COMO UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN COMPUESTO QUE ES INHIBIDOR IRREVERSIBLE DE LAS CINASAS DE LA TIROSINA.
The present invention relates to pyrimido [5,4-d] pyrimidine compounds of Formula II or a pharmaceutically acceptable salt thereof, wherein Q is and X, E1, E2, E3, R6 and p are as defined herein. The compounds of this invention are irreversible inhibitors of tyrosine kinases and are useful in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis.</description><language>spa</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100421&DB=EPODOC&CC=ES&NR=2174250T5$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100421&DB=EPODOC&CC=ES&NR=2174250T5$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DENNY, WILLIAM ALEXANDER</creatorcontrib><creatorcontrib>DOHERTY, ANNETTE, MARIAN</creatorcontrib><creatorcontrib>FRY, DAVID, W</creatorcontrib><creatorcontrib>MCNAMARA, DENNIS, JOSEPH</creatorcontrib><creatorcontrib>DOBRUSIN, ELLEN, MYRA</creatorcontrib><creatorcontrib>BRIDGES, ALEXANDER, JAMES</creatorcontrib><title>INHIBIDORES IRREVERSIBLES DE TIROSINA QUINASAS</title><description>LA PRESENTE INVENCION PROPORCIONA COMPUESTOS QUE SON INHIBIDORES IRREVERSIBLES DE LAS CINASAS DE LA TIROSINA. SE PROPORCIONA IGUALMENTE UN PROCEDIMIENTO PARA TRATAR EL CANCER, LA RESTENOSIS, LA ATEROSCLEROSIS, LA ENDOMETRIOSIS Y EL PSORIASIS, ASI COMO UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN COMPUESTO QUE ES INHIBIDOR IRREVERSIBLE DE LAS CINASAS DE LA TIROSINA.
The present invention relates to pyrimido [5,4-d] pyrimidine compounds of Formula II or a pharmaceutically acceptable salt thereof, wherein Q is and X, E1, E2, E3, R6 and p are as defined herein. The compounds of this invention are irreversible inhibitors of tyrosine kinases and are useful in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDz9PPwdPJ08Q9yDVbwDApyDXMNCvZ08gHyXFwVQjyD_IM9_RwVAkOBZLBjMA8Da1piTnEqL5TmZlB0cw1x9tBNLciPTy0uSExOzUstiXcNNjI0NzEyNQgJMTUmRg0ACpkmbQ</recordid><startdate>20100421</startdate><enddate>20100421</enddate><creator>DENNY, WILLIAM ALEXANDER</creator><creator>DOHERTY, ANNETTE, MARIAN</creator><creator>FRY, DAVID, W</creator><creator>MCNAMARA, DENNIS, JOSEPH</creator><creator>DOBRUSIN, ELLEN, MYRA</creator><creator>BRIDGES, ALEXANDER, JAMES</creator><scope>EVB</scope></search><sort><creationdate>20100421</creationdate><title>INHIBIDORES IRREVERSIBLES DE TIROSINA QUINASAS</title><author>DENNY, WILLIAM ALEXANDER ; DOHERTY, ANNETTE, MARIAN ; FRY, DAVID, W ; MCNAMARA, DENNIS, JOSEPH ; DOBRUSIN, ELLEN, MYRA ; BRIDGES, ALEXANDER, JAMES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2174250TT53</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2010</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DENNY, WILLIAM ALEXANDER</creatorcontrib><creatorcontrib>DOHERTY, ANNETTE, MARIAN</creatorcontrib><creatorcontrib>FRY, DAVID, W</creatorcontrib><creatorcontrib>MCNAMARA, DENNIS, JOSEPH</creatorcontrib><creatorcontrib>DOBRUSIN, ELLEN, MYRA</creatorcontrib><creatorcontrib>BRIDGES, ALEXANDER, JAMES</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DENNY, WILLIAM ALEXANDER</au><au>DOHERTY, ANNETTE, MARIAN</au><au>FRY, DAVID, W</au><au>MCNAMARA, DENNIS, JOSEPH</au><au>DOBRUSIN, ELLEN, MYRA</au><au>BRIDGES, ALEXANDER, JAMES</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INHIBIDORES IRREVERSIBLES DE TIROSINA QUINASAS</title><date>2010-04-21</date><risdate>2010</risdate><abstract>LA PRESENTE INVENCION PROPORCIONA COMPUESTOS QUE SON INHIBIDORES IRREVERSIBLES DE LAS CINASAS DE LA TIROSINA. SE PROPORCIONA IGUALMENTE UN PROCEDIMIENTO PARA TRATAR EL CANCER, LA RESTENOSIS, LA ATEROSCLEROSIS, LA ENDOMETRIOSIS Y EL PSORIASIS, ASI COMO UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN COMPUESTO QUE ES INHIBIDOR IRREVERSIBLE DE LAS CINASAS DE LA TIROSINA.
The present invention relates to pyrimido [5,4-d] pyrimidine compounds of Formula II or a pharmaceutically acceptable salt thereof, wherein Q is and X, E1, E2, E3, R6 and p are as defined herein. The compounds of this invention are irreversible inhibitors of tyrosine kinases and are useful in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | spa |
| recordid | cdi_epo_espacenet_ES2174250TT5 |
| source | esp@cenet |
| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | INHIBIDORES IRREVERSIBLES DE TIROSINA QUINASAS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T14%3A55%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DENNY,%20WILLIAM%20ALEXANDER&rft.date=2010-04-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EES2174250TT5%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |