Set of monocyte I chemically attractive protein inhibitors used for treating e.g. arteriosclerosis comprises natural tricyclic products of fermentation

Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protei...

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Hauptverfasser: VALMASEDA JADU MANUEL, ELSON STEVE W, DIEZ MONEDERO EMILIO, SANCHEZ-PUELLES JOSE MARIA, DE LA FUENTE CARRALERO JESUS, HUESO RODRIGUEZ JUAN ANTONIO
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creator VALMASEDA JADU MANUEL
ELSON STEVE W
DIEZ MONEDERO EMILIO
SANCHEZ-PUELLES JOSE MARIA
DE LA FUENTE CARRALERO JESUS
HUESO RODRIGUEZ JUAN ANTONIO
description Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. (Machine-translation by Google Translate, not legally binding) Productos naturales tricíclicos como inhibidores de la proteína quimioatrayente de monocitos 1. La invención describe un compuesto nuevo de la fórmula (I) y su empleo como un inhibidor de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. También se describe el empleo de los compuestos conocidos en la bibliografía científica como la gunacina y la gunacina saponificada como inhibidores de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. Los compuestos son producidos por la fermentación del hongo Scytalidium flavo-brumeum. Los compuestos son útiles en el tratamiento de ateroesclerosis y otras enfermedades en las cuales se implican la superestimulación de infiltración por monocitos y daño al tejido por macrófagos.
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Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. (Machine-translation by Google Translate, not legally binding) Productos naturales tricíclicos como inhibidores de la proteína quimioatrayente de monocitos 1. La invención describe un compuesto nuevo de la fórmula (I) y su empleo como un inhibidor de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. También se describe el empleo de los compuestos conocidos en la bibliografía científica como la gunacina y la gunacina saponificada como inhibidores de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. Los compuestos son producidos por la fermentación del hongo Scytalidium flavo-brumeum. Los compuestos son útiles en el tratamiento de ateroesclerosis y otras enfermedades en las cuales se implican la superestimulación de infiltración por monocitos y daño al tejido por macrófagos.</description><edition>7</edition><language>eng ; spa</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20011216&amp;DB=EPODOC&amp;CC=ES&amp;NR=2162545A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25571,76555</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20011216&amp;DB=EPODOC&amp;CC=ES&amp;NR=2162545A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VALMASEDA JADU MANUEL</creatorcontrib><creatorcontrib>ELSON STEVE W</creatorcontrib><creatorcontrib>DIEZ MONEDERO EMILIO</creatorcontrib><creatorcontrib>SANCHEZ-PUELLES JOSE MARIA</creatorcontrib><creatorcontrib>DE LA FUENTE CARRALERO JESUS</creatorcontrib><creatorcontrib>HUESO RODRIGUEZ JUAN ANTONIO</creatorcontrib><title>Set of monocyte I chemically attractive protein inhibitors used for treating e.g. arteriosclerosis comprises natural tricyclic products of fermentation</title><description>Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. (Machine-translation by Google Translate, not legally binding) Productos naturales tricíclicos como inhibidores de la proteína quimioatrayente de monocitos 1. La invención describe un compuesto nuevo de la fórmula (I) y su empleo como un inhibidor de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. También se describe el empleo de los compuestos conocidos en la bibliografía científica como la gunacina y la gunacina saponificada como inhibidores de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. Los compuestos son producidos por la fermentación del hongo Scytalidium flavo-brumeum. Los compuestos son útiles en el tratamiento de ateroesclerosis y otras enfermedades en las cuales se implican la superestimulación de infiltración por monocitos y daño al tejido por macrófagos.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjjtuAlEMRaehiIA9eAMg8UuPECipSY-MuQOW3jyPbE-kWUm2G5CygFS3OefovjU_ZyRZS51VkzFBnyQPdCpcykic6Syp36DeLaGVtD70qmkeNARu1JpTOji13gnL-5LYE64WUuAWGiTW9a6BoMo5OJenoDJKUXllb4NkvD608A41nymrs2bScgnM_3ba0On4dfhYoLcLomdBRV6O5_Xqfb3b7varzT-QX_rJUtY</recordid><startdate>20011216</startdate><enddate>20011216</enddate><creator>VALMASEDA JADU MANUEL</creator><creator>ELSON STEVE W</creator><creator>DIEZ MONEDERO EMILIO</creator><creator>SANCHEZ-PUELLES JOSE MARIA</creator><creator>DE LA FUENTE CARRALERO JESUS</creator><creator>HUESO RODRIGUEZ JUAN ANTONIO</creator><scope>EVB</scope></search><sort><creationdate>20011216</creationdate><title>Set of monocyte I chemically attractive protein inhibitors used for treating e.g. arteriosclerosis comprises natural tricyclic products of fermentation</title><author>VALMASEDA JADU MANUEL ; ELSON STEVE W ; DIEZ MONEDERO EMILIO ; SANCHEZ-PUELLES JOSE MARIA ; DE LA FUENTE CARRALERO JESUS ; HUESO RODRIGUEZ JUAN ANTONIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2162545A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2001</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>VALMASEDA JADU MANUEL</creatorcontrib><creatorcontrib>ELSON STEVE W</creatorcontrib><creatorcontrib>DIEZ MONEDERO EMILIO</creatorcontrib><creatorcontrib>SANCHEZ-PUELLES JOSE MARIA</creatorcontrib><creatorcontrib>DE LA FUENTE CARRALERO JESUS</creatorcontrib><creatorcontrib>HUESO RODRIGUEZ JUAN ANTONIO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>VALMASEDA JADU MANUEL</au><au>ELSON STEVE W</au><au>DIEZ MONEDERO EMILIO</au><au>SANCHEZ-PUELLES JOSE MARIA</au><au>DE LA FUENTE CARRALERO JESUS</au><au>HUESO RODRIGUEZ JUAN ANTONIO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Set of monocyte I chemically attractive protein inhibitors used for treating e.g. arteriosclerosis comprises natural tricyclic products of fermentation</title><date>2001-12-16</date><risdate>2001</risdate><abstract>Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products (I). Set of monocyte I chemically-attractive inhibitors comprises natural tricyclic products of formula (I). (I) Are prepared by fermentation of Scytalidum flavo-brumeum and inhibit union in the monocyte I protein and the receptors. (Machine-translation by Google Translate, not legally binding) Productos naturales tricíclicos como inhibidores de la proteína quimioatrayente de monocitos 1. La invención describe un compuesto nuevo de la fórmula (I) y su empleo como un inhibidor de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. También se describe el empleo de los compuestos conocidos en la bibliografía científica como la gunacina y la gunacina saponificada como inhibidores de la unión entre en la proteína quimioatrayente de monocitos 1 y sus receptores. Los compuestos son producidos por la fermentación del hongo Scytalidium flavo-brumeum. Los compuestos son útiles en el tratamiento de ateroesclerosis y otras enfermedades en las cuales se implican la superestimulación de infiltración por monocitos y daño al tejido por macrófagos.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Set of monocyte I chemically attractive protein inhibitors used for treating e.g. arteriosclerosis comprises natural tricyclic products of fermentation
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