DERIVADOS PENTAPEPTIDICOS

Derivados pentapeptídicos, que corresponden a la fórmula (I), en donde E representa -CHO ó -B(OH), y R{sup,1}, R{sup,2}, R{sup,3} R{sup,4}, R{sup,5}, R{sup,6}, R{sup,7}, R{sup,8} y R{sup,9} tienen el significado expuesto en la descripción, y sus sales de compuestos acídicos de fórmula (I) con bases....

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Hauptverfasser: ATTWOOD MICHAEL RICHARD, HURST DAVID NIGEL, RAYNHAM TONY MICHAEL, JONES PHILIP STEPHEN, WILSON FRANCIS XAVIER, KAY PAUL BRITTAIN
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creator ATTWOOD MICHAEL RICHARD
HURST DAVID NIGEL
RAYNHAM TONY MICHAEL
JONES PHILIP STEPHEN
WILSON FRANCIS XAVIER
KAY PAUL BRITTAIN
description Derivados pentapeptídicos, que corresponden a la fórmula (I), en donde E representa -CHO ó -B(OH), y R{sup,1}, R{sup,2}, R{sup,3} R{sup,4}, R{sup,5}, R{sup,6}, R{sup,7}, R{sup,8} y R{sup,9} tienen el significado expuesto en la descripción, y sus sales de compuestos acídicos de fórmula (I) con bases. La invención describe también un procedimiento para la obtención de los referidos compuestos. Los compuestos de la invención se emplean para la producción de medicamentos antivirales, especialmente contra Hepatitis C, Hepatitis G y virus GB humanos. The invention is concerned with amino acid derivatives of the formulaand salts of acidic compounds of formula I with bases, which are viral proteinase inhibitors useful as antiviral agents, especially for the treatment or prophylaxis of infections caused by Hepatitis C, Hepatitis G and human GB viruses.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DERIVADOS PENTAPEPTIDICOS
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