NEW PROCESS FOR PREPARING (-)-TRANS-N-p-FLUOROBENZOYLMETHYL-4-(p-FLUOROPHENYL)-3- 3,4-(METHYLENEDIOXY)PHENOXY]METHYL]-PIPERIDINE

The process consists in reacting (-)-trans-N-(p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo-4'-fluoroacetophenone, and the resulting compound can be isolated as a pharmaceutically acceptable addition salt by reaction with the corresponding...

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Hauptverfasser:	FOGUET AMBROS RAFAEL, GUBERT RIBERA SANTIAGO
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	FOGUET AMBROS RAFAEL GUBERT RIBERA SANTIAGO
description	The process consists in reacting (-)-trans-N-(p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo-4'-fluoroacetophenone, and the resulting compound can be isolated as a pharmaceutically acceptable addition salt by reaction with the corresponding acid. NUEVO PROCEDIMIENTO DE OBTENCION DE (-)-TRANS-N-P-FLUOROBENZOILMETIL-4-(P-FLUOROFENIL)-3-[[3,4-(METILENDIOXI)FENOXI]METIL]-PIPERIDINA. CONSISTE EN HACER REACCIONAR ACETATO DE (-)-TRANS-4-(P-FLUOROFENIL)-3-[[3,4-(METILENDIOXI)FENOXI]METIL]-PIPERIDINA CON 2-CLORO (O BROMO)-4''-FLUORO-ACETOFENONA, PUDIENDOSE AISLAR EL COMPUESTO RESULTANTE COMO SAL DE ADICION FARMACEUTICAMENTE ACEPTABLE POR REACCION CON EL ACIDO CORRESPONDIENTE.
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NUEVO PROCEDIMIENTO DE OBTENCION DE (-)-TRANS-N-P-FLUOROBENZOILMETIL-4-(P-FLUOROFENIL)-3-[[3,4-(METILENDIOXI)FENOXI]METIL]-PIPERIDINA. CONSISTE EN HACER REACCIONAR ACETATO DE (-)-TRANS-4-(P-FLUOROFENIL)-3-[[3,4-(METILENDIOXI)FENOXI]METIL]-PIPERIDINA CON 2-CLORO (O BROMO)-4''-FLUORO-ACETOFENONA, PUDIENDOSE AISLAR EL COMPUESTO RESULTANTE COMO SAL DE ADICION FARMACEUTICAMENTE ACEPTABLE POR REACCION CON EL ACIDO CORRESPONDIENTE.</description><edition>6</edition><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980801&DB=EPODOC&CC=ES&NR=2117557A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980801&DB=EPODOC&CC=ES&NR=2117557A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FOGUET AMBROS RAFAEL</creatorcontrib><creatorcontrib>GUBERT RIBERA SANTIAGO</creatorcontrib><title>NEW PROCESS FOR PREPARING (-)-TRANS-N-p-FLUOROBENZOYLMETHYL-4-(p-FLUOROPHENYL)-3- 3,4-(METHYLENEDIOXY)PHENOXY]METHYL]-PIPERIDINE</title><description>The process consists in reacting (-)-trans-N-(p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo-4'-fluoroacetophenone, and the resulting compound can be isolated as a pharmaceutically acceptable addition salt by reaction with the corresponding acid. NUEVO PROCEDIMIENTO DE OBTENCION DE (-)-TRANS-N-P-FLUOROBENZOILMETIL-4-(P-FLUOROFENIL)-3-[[3,4-(METILENDIOXI)FENOXI]METIL]-PIPERIDINA. 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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title	NEW PROCESS FOR PREPARING (-)-TRANS-N-p-FLUOROBENZOYLMETHYL-4-(p-FLUOROPHENYL)-3- 3,4-(METHYLENEDIOXY)PHENOXY]METHYL]-PIPERIDINE
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