INMUNOADSORBENTES
SE PROPORCIONAN UNOS MEDIOS DE PURIFICACION DE AFINIDAD MEJORADOS MEDIANTE EL USO DE PEQUEÑOS AGENTES DE LIPAZON ESPECIFICOS, SOBRE TODO FRAGMENTO DE ANTICUERPOS FV O FRAGMENTOS DE ANTICUERPOS DE DOMINIO UNICO, INMOVILIZADOS SOBRE TRANSPORTADORES POROSOS QUE TIENEN UN TAMAÑO DE PORO QUE OSCILA ENTRE...
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| creator | DE WINTER, RONALD FRANK JACOBUS VERHOEYEN, MARTINE ELISA DAVIS, PAUL JAMES BERRY, MARK JOHN |
| description | SE PROPORCIONAN UNOS MEDIOS DE PURIFICACION DE AFINIDAD MEJORADOS MEDIANTE EL USO DE PEQUEÑOS AGENTES DE LIPAZON ESPECIFICOS, SOBRE TODO FRAGMENTO DE ANTICUERPOS FV O FRAGMENTOS DE ANTICUERPOS DE DOMINIO UNICO, INMOVILIZADOS SOBRE TRANSPORTADORES POROSOS QUE TIENEN UN TAMAÑO DE PORO QUE OSCILA ENTRE 30-1000 ANGSTROMS, PREFERENTEMENTE 30-300 ANGSTROMS. EL TRANSFORMADOR PREFERIDO ES SILICE. LOS PEQUEÑOS FRAGMENTOS SON CAPACES DE PENETRAR EN LOS POROS Y MAXIMIZAR EL AREA DE SUPERFICIE EFECTIVA DEL TRANSPORTADOR, Y LA SILICE MICROPOROSA ES LO SUFICIENTEMENTE FUERTE COMO PARA SER UTILIZADA A ALTA PRESION, PERMITIENDO ASI EL AUMENTO DE LA VELOCIDAD Y/O RENDIMIENTO DE UN PROCESO DE PURIFICACION.
Improved affinity purification media are provided by the use of small specific binding agents, especially Fv antibody fragments or single domain antibody fragments, immobilised on porous carriers having pore sizes in the range 30-1000 angstroms, preferably 30-300 angstroms. Silica is a preferred carrier. The small fragments are able to penetrate the pores and maximise the effective surface area of the carrier, and the microporous silica is sufficiently robust to be used at high pressure, so enabling the speed and/or throughput of a purification procedure to be increased. |
| format | Patent |
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Improved affinity purification media are provided by the use of small specific binding agents, especially Fv antibody fragments or single domain antibody fragments, immobilised on porous carriers having pore sizes in the range 30-1000 angstroms, preferably 30-300 angstroms. Silica is a preferred carrier. The small fragments are able to penetrate the pores and maximise the effective surface area of the carrier, and the microporous silica is sufficiently robust to be used at high pressure, so enabling the speed and/or throughput of a purification procedure to be increased.</description><edition>6</edition><language>spa</language><subject>BEER ; BIOCHEMISTRY ; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PHYSICS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SEPARATION ; SPIRITS ; TESTING ; THEIR RELEVANT APPARATUS ; TRANSPORTING ; VINEGAR ; WINE</subject><creationdate>1997</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970701&DB=EPODOC&CC=ES&NR=2100875T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970701&DB=EPODOC&CC=ES&NR=2100875T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DE WINTER, RONALD FRANK JACOBUS</creatorcontrib><creatorcontrib>VERHOEYEN, MARTINE ELISA</creatorcontrib><creatorcontrib>DAVIS, PAUL JAMES</creatorcontrib><creatorcontrib>BERRY, MARK JOHN</creatorcontrib><title>INMUNOADSORBENTES</title><description>SE PROPORCIONAN UNOS MEDIOS DE PURIFICACION DE AFINIDAD MEJORADOS MEDIANTE EL USO DE PEQUEÑOS AGENTES DE LIPAZON ESPECIFICOS, SOBRE TODO FRAGMENTO DE ANTICUERPOS FV O FRAGMENTOS DE ANTICUERPOS DE DOMINIO UNICO, INMOVILIZADOS SOBRE TRANSPORTADORES POROSOS QUE TIENEN UN TAMAÑO DE PORO QUE OSCILA ENTRE 30-1000 ANGSTROMS, PREFERENTEMENTE 30-300 ANGSTROMS. EL TRANSFORMADOR PREFERIDO ES SILICE. LOS PEQUEÑOS FRAGMENTOS SON CAPACES DE PENETRAR EN LOS POROS Y MAXIMIZAR EL AREA DE SUPERFICIE EFECTIVA DEL TRANSPORTADOR, Y LA SILICE MICROPOROSA ES LO SUFICIENTEMENTE FUERTE COMO PARA SER UTILIZADA A ALTA PRESION, PERMITIENDO ASI EL AUMENTO DE LA VELOCIDAD Y/O RENDIMIENTO DE UN PROCESO DE PURIFICACION.
Improved affinity purification media are provided by the use of small specific binding agents, especially Fv antibody fragments or single domain antibody fragments, immobilised on porous carriers having pore sizes in the range 30-1000 angstroms, preferably 30-300 angstroms. Silica is a preferred carrier. The small fragments are able to penetrate the pores and maximise the effective surface area of the carrier, and the microporous silica is sufficiently robust to be used at high pressure, so enabling the speed and/or throughput of a purification procedure to be increased.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PHYSICS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SEPARATION</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1997</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBD09PMN9fN3dAn2D3Jy9QtxDeZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfGuwUaGBgYW5qYhIcbGxKgBAENqHng</recordid><startdate>19970701</startdate><enddate>19970701</enddate><creator>DE WINTER, RONALD FRANK JACOBUS</creator><creator>VERHOEYEN, MARTINE ELISA</creator><creator>DAVIS, PAUL JAMES</creator><creator>BERRY, MARK JOHN</creator><scope>EVB</scope></search><sort><creationdate>19970701</creationdate><title>INMUNOADSORBENTES</title><author>DE WINTER, RONALD FRANK JACOBUS ; VERHOEYEN, MARTINE ELISA ; DAVIS, PAUL JAMES ; BERRY, MARK JOHN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2100875TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>1997</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PHYSICS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SEPARATION</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>DE WINTER, RONALD FRANK JACOBUS</creatorcontrib><creatorcontrib>VERHOEYEN, MARTINE ELISA</creatorcontrib><creatorcontrib>DAVIS, PAUL JAMES</creatorcontrib><creatorcontrib>BERRY, MARK JOHN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DE WINTER, RONALD FRANK JACOBUS</au><au>VERHOEYEN, MARTINE ELISA</au><au>DAVIS, PAUL JAMES</au><au>BERRY, MARK JOHN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INMUNOADSORBENTES</title><date>1997-07-01</date><risdate>1997</risdate><abstract>SE PROPORCIONAN UNOS MEDIOS DE PURIFICACION DE AFINIDAD MEJORADOS MEDIANTE EL USO DE PEQUEÑOS AGENTES DE LIPAZON ESPECIFICOS, SOBRE TODO FRAGMENTO DE ANTICUERPOS FV O FRAGMENTOS DE ANTICUERPOS DE DOMINIO UNICO, INMOVILIZADOS SOBRE TRANSPORTADORES POROSOS QUE TIENEN UN TAMAÑO DE PORO QUE OSCILA ENTRE 30-1000 ANGSTROMS, PREFERENTEMENTE 30-300 ANGSTROMS. EL TRANSFORMADOR PREFERIDO ES SILICE. LOS PEQUEÑOS FRAGMENTOS SON CAPACES DE PENETRAR EN LOS POROS Y MAXIMIZAR EL AREA DE SUPERFICIE EFECTIVA DEL TRANSPORTADOR, Y LA SILICE MICROPOROSA ES LO SUFICIENTEMENTE FUERTE COMO PARA SER UTILIZADA A ALTA PRESION, PERMITIENDO ASI EL AUMENTO DE LA VELOCIDAD Y/O RENDIMIENTO DE UN PROCESO DE PURIFICACION.
Improved affinity purification media are provided by the use of small specific binding agents, especially Fv antibody fragments or single domain antibody fragments, immobilised on porous carriers having pore sizes in the range 30-1000 angstroms, preferably 30-300 angstroms. Silica is a preferred carrier. The small fragments are able to penetrate the pores and maximise the effective surface area of the carrier, and the microporous silica is sufficiently robust to be used at high pressure, so enabling the speed and/or throughput of a purification procedure to be increased.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SEPARATION SPIRITS TESTING THEIR RELEVANT APPARATUS TRANSPORTING VINEGAR WINE |
| title | INMUNOADSORBENTES |
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