DERIVADOS DE ACIDO MANDELICO SUBSTITUIDOS COMO INHIBIDORES DE 5-LIPOXIGENASA

LOS DERIVADOS DEL ACIDO MANDELICO SUSTITUIDO SE PUEDEN FABRICAR POR CONVERSION DE ESTERES GLIOXILICOS CON COMPUESTOS GRIGNARD. LOS DERIVADOS DEL ACIDO MANDELICO SUSTITUIDO SON APROPIADOS COMO SUSTANCIAS ACTIVAS EN PRODUCTOS FARMACEUTICOS, EN PARTICULAR, PARA PRODUCTOS FARMACEUTICOS INHIBIDORES DE LA...

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Hauptverfasser: FRUCHTMANN, ROMANIS, KOHLSDORFER, CHRISTIAN, HATZELMANN, ARMIN, MULLER-PEDDINGHAUS, REINER, DR, MATZKE, MICHAEL, THEISEN-POPP, PIA, RADDATZ, SIEGFRIED, MOHRS, KLAUS-HELMUT
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creator FRUCHTMANN, ROMANIS
KOHLSDORFER, CHRISTIAN
HATZELMANN, ARMIN
MULLER-PEDDINGHAUS, REINER, DR
MATZKE, MICHAEL
THEISEN-POPP, PIA
RADDATZ, SIEGFRIED
MOHRS, KLAUS-HELMUT
description LOS DERIVADOS DEL ACIDO MANDELICO SUSTITUIDO SE PUEDEN FABRICAR POR CONVERSION DE ESTERES GLIOXILICOS CON COMPUESTOS GRIGNARD. LOS DERIVADOS DEL ACIDO MANDELICO SUSTITUIDO SON APROPIADOS COMO SUSTANCIAS ACTIVAS EN PRODUCTOS FARMACEUTICOS, EN PARTICULAR, PARA PRODUCTOS FARMACEUTICOS INHIBIDORES DE LA SINTESIS DEL LEUCOTRIENO. Substituted mandelic acid derivatives can be prepared by reaction of glyoxylic esters with Grignard compounds. The substituted mandelic acid derivatives are suitable as active compounds in medicaments, in particular for medicaments which inhibit leukotriene synthesis.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DERIVADOS DE ACIDO MANDELICO SUBSTITUIDOS COMO INHIBIDORES DE 5-LIPOXIGENASA
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