UN METODO DE PREPARACION DE UN CONCENTRADO DE FIBRINOGENO A PARTIR DE PLASMA SANGUINEO, UN DISPOSITIVO PARA LLEVAR A CABO DICHO METODO, Y UN METODO DE PREPARACION DE FIBRINOGENO A PARTIR DE DICHO CONCENTRADO
ES UN METODO DE PREPARACION DE CONCENTRADO DE FIBRINOGENO A PARTIR DEL PLASMA SANGUINEO, MEDIANTE EL ENFRIAMIENTO DE DICHO PLASMA DE UNA TEMPERATURA POR ENCIMA DE LOS 0 C HASTA UNA TEMPERATURA INICIAL ENTRE -10 C Y -40 C, DERRITIENDOSE LA SUSTANCIA SOLIDA ASI OBTENIDA HASTA UNA TEMPERATURA CERCANA A...
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| creator | WIJNGAARDS, GERRIT VAN DOMMELEN, FREDERIK SUSAN |
| description | ES UN METODO DE PREPARACION DE CONCENTRADO DE FIBRINOGENO A PARTIR DEL PLASMA SANGUINEO, MEDIANTE EL ENFRIAMIENTO DE DICHO PLASMA DE UNA TEMPERATURA POR ENCIMA DE LOS 0 C HASTA UNA TEMPERATURA INICIAL ENTRE -10 C Y -40 C, DERRITIENDOSE LA SUSTANCIA SOLIDA ASI OBTENIDA HASTA UNA TEMPERATURA CERCANA AL PUNTO DE CONGELACION DEL AGUA, Y POR CONSIGUIENTE, SEPARANDO FISICAMENTE LA MATERIA SOLIDA Y LA FRACCION LIQUIDA PRINCIPAL DEL PLASMA, ES DECIR, EL AGUA. DE ESTA MANERA LA DESCONGELACION SE EFECTUA EN FASES DESDE LA TEMPERATURA INICIAL HASTA UNA TEMPERATURA DETERMINADA ENTRE -5 C Y -1 C, DESPUES DE LO CUAL EL VOLUMEN DEL MATERIAL SOLIDO SE REDUCE, Y ESTE MATERIAL REDUCIDO SE LLEVA HASTA UNA TEMPERATURA EN LA CUAL LA FRACCION PRINCIPAL DEL PLASMA, ES DECIR EL AGUA, SE CONVIERTE EN LIQUIDO Y LA SOLUBILIDAD DEL FIBRINOGENO EN DICHO FLUIDO SERA TAN BAJA COMO SEA POSIBLE. DESPUES DE ESTO, EL LIQUIDO SE SEPARA DEL CONCENTRADO DE FIBRINOGENO. LA INVENCION TAMBIEN DESCRIBE UN MECANISMO PARA LLEVAR A CABO ESTE METODO.
A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separating the solid matter and the liquid main fraction of the plasma, viz. water, whereby the thawing is effected in steps from the first temperature to a conditioning temperature between -5 DEG C and -1 DEG C, after which the size of the solid material is reduced and the reduced material is brought to a temperature at which the main fraction of the plasma, viz. water, becomes liquid and the solubility of fibrinogen in said fluid is as low as possible, after which fluid is separated from the fibrinogen concentrate. The invention also relates to a device for carrying out this method. |
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A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separating the solid matter and the liquid main fraction of the plasma, viz. water, whereby the thawing is effected in steps from the first temperature to a conditioning temperature between -5 DEG C and -1 DEG C, after which the size of the solid material is reduced and the reduced material is brought to a temperature at which the main fraction of the plasma, viz. water, becomes liquid and the solubility of fibrinogen in said fluid is as low as possible, after which fluid is separated from the fibrinogen concentrate. The invention also relates to a device for carrying out this method.</description><edition>4</edition><language>spa</language><subject>CHEMISTRY ; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY ; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR ; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY ; FOODS OR FOODSTUFFS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROTEIN COMPOSITIONS FOR FOODSTUFFS ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES ; WORKING-UP PROTEINS FOR FOODSTUFFS</subject><creationdate>1994</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941101&DB=EPODOC&CC=ES&NR=2059031T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941101&DB=EPODOC&CC=ES&NR=2059031T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WIJNGAARDS, GERRIT</creatorcontrib><creatorcontrib>VAN DOMMELEN, FREDERIK SUSAN</creatorcontrib><title>UN METODO DE PREPARACION DE UN CONCENTRADO DE FIBRINOGENO A PARTIR DE PLASMA SANGUINEO, UN DISPOSITIVO PARA LLEVAR A CABO DICHO METODO, Y UN METODO DE PREPARACION DE FIBRINOGENO A PARTIR DE DICHO CONCENTRADO</title><description>ES UN METODO DE PREPARACION DE CONCENTRADO DE FIBRINOGENO A PARTIR DEL PLASMA SANGUINEO, MEDIANTE EL ENFRIAMIENTO DE DICHO PLASMA DE UNA TEMPERATURA POR ENCIMA DE LOS 0 C HASTA UNA TEMPERATURA INICIAL ENTRE -10 C Y -40 C, DERRITIENDOSE LA SUSTANCIA SOLIDA ASI OBTENIDA HASTA UNA TEMPERATURA CERCANA AL PUNTO DE CONGELACION DEL AGUA, Y POR CONSIGUIENTE, SEPARANDO FISICAMENTE LA MATERIA SOLIDA Y LA FRACCION LIQUIDA PRINCIPAL DEL PLASMA, ES DECIR, EL AGUA. DE ESTA MANERA LA DESCONGELACION SE EFECTUA EN FASES DESDE LA TEMPERATURA INICIAL HASTA UNA TEMPERATURA DETERMINADA ENTRE -5 C Y -1 C, DESPUES DE LO CUAL EL VOLUMEN DEL MATERIAL SOLIDO SE REDUCE, Y ESTE MATERIAL REDUCIDO SE LLEVA HASTA UNA TEMPERATURA EN LA CUAL LA FRACCION PRINCIPAL DEL PLASMA, ES DECIR EL AGUA, SE CONVIERTE EN LIQUIDO Y LA SOLUBILIDAD DEL FIBRINOGENO EN DICHO FLUIDO SERA TAN BAJA COMO SEA POSIBLE. DESPUES DE ESTO, EL LIQUIDO SE SEPARA DEL CONCENTRADO DE FIBRINOGENO. LA INVENCION TAMBIEN DESCRIBE UN MECANISMO PARA LLEVAR A CABO ESTE METODO.
A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separating the solid matter and the liquid main fraction of the plasma, viz. water, whereby the thawing is effected in steps from the first temperature to a conditioning temperature between -5 DEG C and -1 DEG C, after which the size of the solid material is reduced and the reduced material is brought to a temperature at which the main fraction of the plasma, viz. water, becomes liquid and the solubility of fibrinogen in said fluid is as low as possible, after which fluid is separated from the fibrinogen concentrate. The invention also relates to a device for carrying out this method.</description><subject>CHEMISTRY</subject><subject>DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY</subject><subject>DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR</subject><subject>DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY</subject><subject>FOODS OR FOODSTUFFS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROTEIN COMPOSITIONS FOR FOODSTUFFS</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><subject>WORKING-UP PROTEINS FOR FOODSTUFFS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1994</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjj0KwkAQhdNYiHqHsY8QDRaWk80kGYg7YXcTsApB1kpU0Ht6JRO1sFGshsd872cc3GsNW3KSCqQElaEKDSoWPcj-p0Qr0s7gC8g4MawlJy2A0LOOzdNYot0iWNR5zZokHLwp20osO25kQBHKkho0vVFh0sexKuRdHsIOfi351vvK-Bg5DUaH7nj1s_edBPOMnCoW_nJu_fXS7f3J31qyq2i9ieKlc3H8D_MAP_tQuA</recordid><startdate>19941101</startdate><enddate>19941101</enddate><creator>WIJNGAARDS, GERRIT</creator><creator>VAN DOMMELEN, FREDERIK SUSAN</creator><scope>EVB</scope></search><sort><creationdate>19941101</creationdate><title>UN METODO DE PREPARACION DE UN CONCENTRADO DE FIBRINOGENO A PARTIR DE PLASMA SANGUINEO, UN DISPOSITIVO PARA LLEVAR A CABO DICHO METODO, Y UN METODO DE PREPARACION DE FIBRINOGENO A PARTIR DE DICHO CONCENTRADO</title><author>WIJNGAARDS, GERRIT ; VAN DOMMELEN, FREDERIK SUSAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2059031TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>1994</creationdate><topic>CHEMISTRY</topic><topic>DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY</topic><topic>DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR</topic><topic>DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY</topic><topic>FOODS OR FOODSTUFFS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROTEIN COMPOSITIONS FOR FOODSTUFFS</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><topic>WORKING-UP PROTEINS FOR FOODSTUFFS</topic><toplevel>online_resources</toplevel><creatorcontrib>WIJNGAARDS, GERRIT</creatorcontrib><creatorcontrib>VAN DOMMELEN, FREDERIK SUSAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WIJNGAARDS, GERRIT</au><au>VAN DOMMELEN, FREDERIK SUSAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>UN METODO DE PREPARACION DE UN CONCENTRADO DE FIBRINOGENO A PARTIR DE PLASMA SANGUINEO, UN DISPOSITIVO PARA LLEVAR A CABO DICHO METODO, Y UN METODO DE PREPARACION DE FIBRINOGENO A PARTIR DE DICHO CONCENTRADO</title><date>1994-11-01</date><risdate>1994</risdate><abstract>ES UN METODO DE PREPARACION DE CONCENTRADO DE FIBRINOGENO A PARTIR DEL PLASMA SANGUINEO, MEDIANTE EL ENFRIAMIENTO DE DICHO PLASMA DE UNA TEMPERATURA POR ENCIMA DE LOS 0 C HASTA UNA TEMPERATURA INICIAL ENTRE -10 C Y -40 C, DERRITIENDOSE LA SUSTANCIA SOLIDA ASI OBTENIDA HASTA UNA TEMPERATURA CERCANA AL PUNTO DE CONGELACION DEL AGUA, Y POR CONSIGUIENTE, SEPARANDO FISICAMENTE LA MATERIA SOLIDA Y LA FRACCION LIQUIDA PRINCIPAL DEL PLASMA, ES DECIR, EL AGUA. DE ESTA MANERA LA DESCONGELACION SE EFECTUA EN FASES DESDE LA TEMPERATURA INICIAL HASTA UNA TEMPERATURA DETERMINADA ENTRE -5 C Y -1 C, DESPUES DE LO CUAL EL VOLUMEN DEL MATERIAL SOLIDO SE REDUCE, Y ESTE MATERIAL REDUCIDO SE LLEVA HASTA UNA TEMPERATURA EN LA CUAL LA FRACCION PRINCIPAL DEL PLASMA, ES DECIR EL AGUA, SE CONVIERTE EN LIQUIDO Y LA SOLUBILIDAD DEL FIBRINOGENO EN DICHO FLUIDO SERA TAN BAJA COMO SEA POSIBLE. DESPUES DE ESTO, EL LIQUIDO SE SEPARA DEL CONCENTRADO DE FIBRINOGENO. LA INVENCION TAMBIEN DESCRIBE UN MECANISMO PARA LLEVAR A CABO ESTE METODO.
A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 DEG C to a first temperature between -10 DEG C and -40 DEG C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separating the solid matter and the liquid main fraction of the plasma, viz. water, whereby the thawing is effected in steps from the first temperature to a conditioning temperature between -5 DEG C and -1 DEG C, after which the size of the solid material is reduced and the reduced material is brought to a temperature at which the main fraction of the plasma, viz. water, becomes liquid and the solubility of fibrinogen in said fluid is as low as possible, after which fluid is separated from the fibrinogen concentrate. The invention also relates to a device for carrying out this method.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY FOODS OR FOODSTUFFS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROTEIN COMPOSITIONS FOR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES WORKING-UP PROTEINS FOR FOODSTUFFS |
| title | UN METODO DE PREPARACION DE UN CONCENTRADO DE FIBRINOGENO A PARTIR DE PLASMA SANGUINEO, UN DISPOSITIVO PARA LLEVAR A CABO DICHO METODO, Y UN METODO DE PREPARACION DE FIBRINOGENO A PARTIR DE DICHO CONCENTRADO |
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