DERIVADOS 2-AMINOPIRIMIDINONA

NUEVOS DERIVADOS DE 2-AMINOPIRIMIDINONA DE LA FORMULA EN DONDE R1 ES R3 ES HIDROGENO O C1-6ALQUILO; R4 ES HIDROGENO, C1-6ALQUILO, O C1-6ALQUILO SUSTITUIDO; R5 ES HIDROGENO, C-16ALQUILO, C1-6ALQUILAMINOCARBONILO, AR-AMINOCARBONILO, C1-6ALQUILCARBONILO O AR-CARBONILO; R6 ES HIDROGENO, C1-6ALQUILO O AR...

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Hauptverfasser: VANDENBERK, JAN, BOEY, JOZEF M, KENNIS, LUDO E. J
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BOEY, JOZEF M
KENNIS, LUDO E. J
description NUEVOS DERIVADOS DE 2-AMINOPIRIMIDINONA DE LA FORMULA EN DONDE R1 ES R3 ES HIDROGENO O C1-6ALQUILO; R4 ES HIDROGENO, C1-6ALQUILO, O C1-6ALQUILO SUSTITUIDO; R5 ES HIDROGENO, C-16ALQUILO, C1-6ALQUILAMINOCARBONILO, AR-AMINOCARBONILO, C1-6ALQUILCARBONILO O AR-CARBONILO; R6 ES HIDROGENO, C1-6ALQUILO O AR-C1-6ALQUILO; O R5 Y R6 JUNTOS SON -CH2-CH2-, -CH2-CH2-CH2-, -CH = CH-, -CH = N-, -N = CH- O -N = CH-CH2-; LAS SALES DE ADICION ACIDAS FARMACEUTICAMENTE ACEPTABLES Y SUS FORMAS POSIBLES ESTEREOQUIMICAMENTE ISOMERICAS; COMPOSICIONES FARMACEUTICAS QUE CONTENGAN DICHOS COMPUESTOS COMO INGREDIENTE ACTIVO Y METODOS DE PREPARACION DE DICHOS COMPUESTOS Y COMPOSICIONES FARMACEUTICAS. Novel 2-aminopyrimidinone derivatives of formula wherein R is R is hydrogen or C1-6alkyl; R is hydrogen, C1-6alkyl or substituted C1-6alkyl; R is hydrogen, C1-6alkyl, C1-6alkylaminocarbonyl, Ar-aminocarbonyl, C1-6alkylcarbonyl or Ar-carbonyl; R is hydrogen, C1-6alkyl or Ar-C1-6alkyl; or R and R taken together is -CH2-CH2-, -CH2-CH2-CH2-, -CH=CH-, -CH=N-, -N=CH- or -N=CH-CH2-; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
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Novel 2-aminopyrimidinone derivatives of formula wherein R is R is hydrogen or C1-6alkyl; R is hydrogen, C1-6alkyl or substituted C1-6alkyl; R is hydrogen, C1-6alkyl, C1-6alkylaminocarbonyl, Ar-aminocarbonyl, C1-6alkylcarbonyl or Ar-carbonyl; R is hydrogen, C1-6alkyl or Ar-C1-6alkyl; or R and R taken together is -CH2-CH2-, -CH2-CH2-CH2-, -CH=CH-, -CH=N-, -N=CH- or -N=CH-CH2-; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.</description><edition>4</edition><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1994</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19940901&amp;DB=EPODOC&amp;CC=ES&amp;NR=2055860T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25555,76308</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19940901&amp;DB=EPODOC&amp;CC=ES&amp;NR=2055860T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VANDENBERK, JAN</creatorcontrib><creatorcontrib>BOEY, JOZEF M</creatorcontrib><creatorcontrib>KENNIS, LUDO E. 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Novel 2-aminopyrimidinone derivatives of formula wherein R is R is hydrogen or C1-6alkyl; R is hydrogen, C1-6alkyl or substituted C1-6alkyl; R is hydrogen, C1-6alkyl, C1-6alkylaminocarbonyl, Ar-aminocarbonyl, C1-6alkylcarbonyl or Ar-carbonyl; R is hydrogen, C1-6alkyl or Ar-C1-6alkyl; or R and R taken together is -CH2-CH2-, -CH2-CH2-CH2-, -CH=CH-, -CH=N-, -N=CH- or -N=CH-CH2-; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1994</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJB1cQ3yDHN08Q9WMNJ19PX08w_wDPL09XQBsvwceRhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYnJqXmpJvGuwkYGpqYWZQUiIsTExagCfgyGR</recordid><startdate>19940901</startdate><enddate>19940901</enddate><creator>VANDENBERK, JAN</creator><creator>BOEY, JOZEF M</creator><creator>KENNIS, LUDO E. J</creator><scope>EVB</scope></search><sort><creationdate>19940901</creationdate><title>DERIVADOS 2-AMINOPIRIMIDINONA</title><author>VANDENBERK, JAN ; BOEY, JOZEF M ; KENNIS, LUDO E. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2055860TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>1994</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>VANDENBERK, JAN</creatorcontrib><creatorcontrib>BOEY, JOZEF M</creatorcontrib><creatorcontrib>KENNIS, LUDO E. 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J</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVADOS 2-AMINOPIRIMIDINONA</title><date>1994-09-01</date><risdate>1994</risdate><abstract>NUEVOS DERIVADOS DE 2-AMINOPIRIMIDINONA DE LA FORMULA EN DONDE R1 ES R3 ES HIDROGENO O C1-6ALQUILO; R4 ES HIDROGENO, C1-6ALQUILO, O C1-6ALQUILO SUSTITUIDO; R5 ES HIDROGENO, C-16ALQUILO, C1-6ALQUILAMINOCARBONILO, AR-AMINOCARBONILO, C1-6ALQUILCARBONILO O AR-CARBONILO; R6 ES HIDROGENO, C1-6ALQUILO O AR-C1-6ALQUILO; O R5 Y R6 JUNTOS SON -CH2-CH2-, -CH2-CH2-CH2-, -CH = CH-, -CH = N-, -N = CH- O -N = CH-CH2-; LAS SALES DE ADICION ACIDAS FARMACEUTICAMENTE ACEPTABLES Y SUS FORMAS POSIBLES ESTEREOQUIMICAMENTE ISOMERICAS; COMPOSICIONES FARMACEUTICAS QUE CONTENGAN DICHOS COMPUESTOS COMO INGREDIENTE ACTIVO Y METODOS DE PREPARACION DE DICHOS COMPUESTOS Y COMPOSICIONES FARMACEUTICAS. Novel 2-aminopyrimidinone derivatives of formula wherein R is R is hydrogen or C1-6alkyl; R is hydrogen, C1-6alkyl or substituted C1-6alkyl; R is hydrogen, C1-6alkyl, C1-6alkylaminocarbonyl, Ar-aminocarbonyl, C1-6alkylcarbonyl or Ar-carbonyl; R is hydrogen, C1-6alkyl or Ar-C1-6alkyl; or R and R taken together is -CH2-CH2-, -CH2-CH2-CH2-, -CH=CH-, -CH=N-, -N=CH- or -N=CH-CH2-; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DERIVADOS 2-AMINOPIRIMIDINONA
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