TISSUE MATURATION BIOREACTOR SYSTEMS WITH UNIFORM CELL DISTRIBUTION

System and method for exercising cells and/or tissue in a sealed bioreactor. System includes a cartridge having a stretching means and a means to retain cells on a scaffold mounted within the cartridge during seeding. System includes a bioreactor including a sealed enclosure, the sealed enclosure ho...

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Bibliographische Detailangaben
Hauptverfasser:	TILLEY, Michael C, CAPULLI, Andrew K, JACOBSON, Stuart A, KOPS, Zachary T, NESBITT, Jamie L, MCGRATH, Keira L
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	System and method for exercising cells and/or tissue in a sealed bioreactor. System includes a cartridge having a stretching means and a means to retain cells on a scaffold mounted within the cartridge during seeding. System includes a bioreactor including a sealed enclosure, the sealed enclosure housing the scaffold and the cartridge, the bioreactor enabling uniform seeding of the scaffold with the cells, the seeding occurring within the sealed enclosure to protect from environmental contamination. The bioreactor system provides a means to supply fresh media to the cells and/or tissue, and a means to remove waste products.