NON-IMMUNOSUPPRESSIVE FK506 ANALOGS AND USE THEREOF

The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds.

Bibliographische Detailangaben

Hauptverfasser:	GUO, Zufeng, AHMADI, Ali, LIU, Jun O, PENG, Hanjing, SUN, Zhaoli, QI, Le, WANG, Yuefan, PEIFFER, Brandon J
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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