NOVEL THYROID PEROXIDASE AUTOANTIBODY IMMUNOASSAY

NOVEL THYROID PEROXIDASE AUTOANTIBODY IMMUNOASSAY

Disclosed herein are immunoassays for detecting an anti-thyroid peroxidase antibody in a biological sample from a subject and/or diagnosing a thyroid disease in a subject. The disclosed immunoassays employ a recombinant cynomolgus monkey thyroid peroxidase (rTPO) and assess the level of anti-thyroid...

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Hauptverfasser: Cherian, Saji, Tewari, Prakash, Lee, Haekyung, Hammarquist, Gabriel, Han, Aili, D'Agostino, Paul, Jaggi, Kuldeep, Cortese, Kayla, Sahakian, Niver, Poladian, Maral, Sinha, Seema
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Cherian, Saji
Tewari, Prakash
Lee, Haekyung
Hammarquist, Gabriel
Han, Aili
D'Agostino, Paul
Jaggi, Kuldeep
Cortese, Kayla
Sahakian, Niver
Poladian, Maral
Sinha, Seema
description Disclosed herein are immunoassays for detecting an anti-thyroid peroxidase antibody in a biological sample from a subject and/or diagnosing a thyroid disease in a subject. The disclosed immunoassays employ a recombinant cynomolgus monkey thyroid peroxidase (rTPO) and assess the level of anti-thyroid peroxidase antibody-induced formation or disruption of complexes comprising a solid support and the rTPO.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title NOVEL THYROID PEROXIDASE AUTOANTIBODY IMMUNOASSAY
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