COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF PREKALLIKREIN (PKK) PROTEIN

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF PREKALLIKREIN (PKK) PROTEIN

Compositions and methods useful to reduce expression of a kallikrein B1 (KLKB1 or PKK) gene and for treatment of PKK-associated diseases and conditions are provided. Provided are PKK dsRNA agents, and compositions comprising PKK dsRNA agents that can be used to reduce PKK expression in cells and sub...

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Bibliographische Detailangaben
Hauptverfasser: XIA, Shiwei, SHAO, Pengcheng, Patrick, SHU, Dongxu
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Compositions and methods useful to reduce expression of a kallikrein B1 (KLKB1 or PKK) gene and for treatment of PKK-associated diseases and conditions are provided. Provided are PKK dsRNA agents, and compositions comprising PKK dsRNA agents that can be used to reduce PKK expression in cells and subjects.