OXAZOLE DERIVATIVE COMPOUND HAVING ANTIBACTERIAL ACTIVITY AND MEDICAL USE THEREOF

The present disclosure provides a novel oxazole derivative compound having anti-Mycobacterium tuberculosis activity or a pharmaceutically acceptable salt thereof. The present disclosure also provides an antibacterial composition comprising the compound or a pharmaceutically acceptable salt thereof....

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Hauptverfasser: KIM, Young Mi, AHN, Ji Eun, SON, Eunsoon, JEONG, Mi Ji, KIM, Kyungjong, YANG, Jeong Seong, LEE, Ji-im, PARK, Yumi, LEE, Aram, LEE, Jong Seok, WHANG, Jake, CUI, Lianji, CHOI, Inhee
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creator KIM, Young Mi
AHN, Ji Eun
SON, Eunsoon
JEONG, Mi Ji
KIM, Kyungjong
YANG, Jeong Seong
LEE, Ji-im
PARK, Yumi
LEE, Aram
LEE, Jong Seok
WHANG, Jake
CUI, Lianji
CHOI, Inhee
description The present disclosure provides a novel oxazole derivative compound having anti-Mycobacterium tuberculosis activity or a pharmaceutically acceptable salt thereof. The present disclosure also provides an antibacterial composition comprising the compound or a pharmaceutically acceptable salt thereof. The novel oxazole compound according to the present disclosure has remarkably excellent antibacterial activity, particularly anti-Mycobacterium tuberculosis activity, and thus can be effectively used in the prevention or treatment of diseases caused by bacterial infection.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title OXAZOLE DERIVATIVE COMPOUND HAVING ANTIBACTERIAL ACTIVITY AND MEDICAL USE THEREOF
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