BODIPY-BASED DYES FOR DIGITAL SPATIAL PROTEOMICS

The disclosure provides probes comprising dipyrromethane-BF2 derivatives which exhibits different fluorescent spectral properties when conjugated to the amino acids, compositions and kits comprising same. The disclosure also provides methods for detecting/identifying amino acids and sequencing polyp...

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Hauptverfasser: CHEN, Ichun Anderson, BEELER, Aaron Beaty, EMILI, Andrew, LENIHAN, Jason Michael, HENDRICK, Nathaniel Ryan
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creator CHEN, Ichun Anderson
BEELER, Aaron Beaty
EMILI, Andrew
LENIHAN, Jason Michael
HENDRICK, Nathaniel Ryan
description The disclosure provides probes comprising dipyrromethane-BF2 derivatives which exhibits different fluorescent spectral properties when conjugated to the amino acids, compositions and kits comprising same. The disclosure also provides methods for detecting/identifying amino acids and sequencing polypeptide molecules by conjugating a dipyrromethane-BF2 derivative which exhibits different fluorescent spectral properties when conjugated to the amino acids.
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language eng ; fre ; ger
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PHYSICS
TESTING
title BODIPY-BASED DYES FOR DIGITAL SPATIAL PROTEOMICS
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