ADENOVIRAL VECTORS

Disclosed herein is an adenoviral vector system utilizing DARPin adapters. The system is highly effective, safe and able to deliver DNA in a cell-specific manner. It is demonstrated that the system is unexpectedly versatile, and can be used in conjunction with protein scaffolds, bioactive peptides a...

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Bibliographische Detailangaben
Hauptverfasser: SMITH, Sheena Nichole, BRÜCHER, Dominik, DREIER, Birgit, PLÜCKTHUN, Andreas, FREITAG, Patrick Christian, BRANDL, Fabian, WEISS, Fabian
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed herein is an adenoviral vector system utilizing DARPin adapters. The system is highly effective, safe and able to deliver DNA in a cell-specific manner. It is demonstrated that the system is unexpectedly versatile, and can be used in conjunction with protein scaffolds, bioactive peptides and small molecules. This makes the system useful for numerous purposes, including the use of the system for therapeutic and diagnostic purposes.