ANTIBODY DRUG CONJUGATES AND METHODS FOR MAKING THEREOF

This application discloses microorganisms and methods of producing GNAQ/GNA11 inhibitors and methods of making antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The disclosure also relates to formulations comprising antibody drug co...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: D'ALESSIO, Joseph Anthony, IYER, Shwetha, MAUDENS, Pierre, HAINZL, Dominik, KHERA, Eshita, FESSLER, Boris, FAN, Liqiong, MANCHADO ROBLES, Eusebio, BLUEMMEL, Anne-Sophie, GABRIEL, Doris, YERRAMILLI-RAO, Padmaja, WUERSCH, Kuno, PISTORIUS, Dominik, HOFFMASTER, Keith, ROMANET, Vincent, RAMOT, Roee, BUNTIN, Kathrin
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator D'ALESSIO, Joseph Anthony
IYER, Shwetha
MAUDENS, Pierre
HAINZL, Dominik
KHERA, Eshita
FESSLER, Boris
FAN, Liqiong
MANCHADO ROBLES, Eusebio
BLUEMMEL, Anne-Sophie
GABRIEL, Doris
YERRAMILLI-RAO, Padmaja
WUERSCH, Kuno
PISTORIUS, Dominik
HOFFMASTER, Keith
ROMANET, Vincent
RAMOT, Roee
BUNTIN, Kathrin
description This application discloses microorganisms and methods of producing GNAQ/GNA11 inhibitors and methods of making antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The disclosure also relates to formulations comprising antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor and methods of treating or preventing cancer using the formulations.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4427590A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4427590A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4427590A23</originalsourceid><addsrcrecordid>eNrjZDB39AvxdPJ3iVRwCQp1V3D29_MKdXcMcQ1WcPRzUfB1DfHwdwlWcPMPUvB19Pb0c1cI8XANcvV342FgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BJiZG5qaWBo5GxkQoAQDkBSe3</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ANTIBODY DRUG CONJUGATES AND METHODS FOR MAKING THEREOF</title><source>esp@cenet</source><creator>D'ALESSIO, Joseph Anthony ; IYER, Shwetha ; MAUDENS, Pierre ; HAINZL, Dominik ; KHERA, Eshita ; FESSLER, Boris ; FAN, Liqiong ; MANCHADO ROBLES, Eusebio ; BLUEMMEL, Anne-Sophie ; GABRIEL, Doris ; YERRAMILLI-RAO, Padmaja ; WUERSCH, Kuno ; PISTORIUS, Dominik ; HOFFMASTER, Keith ; ROMANET, Vincent ; RAMOT, Roee ; BUNTIN, Kathrin</creator><creatorcontrib>D'ALESSIO, Joseph Anthony ; IYER, Shwetha ; MAUDENS, Pierre ; HAINZL, Dominik ; KHERA, Eshita ; FESSLER, Boris ; FAN, Liqiong ; MANCHADO ROBLES, Eusebio ; BLUEMMEL, Anne-Sophie ; GABRIEL, Doris ; YERRAMILLI-RAO, Padmaja ; WUERSCH, Kuno ; PISTORIUS, Dominik ; HOFFMASTER, Keith ; ROMANET, Vincent ; RAMOT, Roee ; BUNTIN, Kathrin</creatorcontrib><description>This application discloses microorganisms and methods of producing GNAQ/GNA11 inhibitors and methods of making antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The disclosure also relates to formulations comprising antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor and methods of treating or preventing cancer using the formulations.</description><language>eng ; fre ; ger</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; TRAPPING</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240911&amp;DB=EPODOC&amp;CC=EP&amp;NR=4427590A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240911&amp;DB=EPODOC&amp;CC=EP&amp;NR=4427590A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>D'ALESSIO, Joseph Anthony</creatorcontrib><creatorcontrib>IYER, Shwetha</creatorcontrib><creatorcontrib>MAUDENS, Pierre</creatorcontrib><creatorcontrib>HAINZL, Dominik</creatorcontrib><creatorcontrib>KHERA, Eshita</creatorcontrib><creatorcontrib>FESSLER, Boris</creatorcontrib><creatorcontrib>FAN, Liqiong</creatorcontrib><creatorcontrib>MANCHADO ROBLES, Eusebio</creatorcontrib><creatorcontrib>BLUEMMEL, Anne-Sophie</creatorcontrib><creatorcontrib>GABRIEL, Doris</creatorcontrib><creatorcontrib>YERRAMILLI-RAO, Padmaja</creatorcontrib><creatorcontrib>WUERSCH, Kuno</creatorcontrib><creatorcontrib>PISTORIUS, Dominik</creatorcontrib><creatorcontrib>HOFFMASTER, Keith</creatorcontrib><creatorcontrib>ROMANET, Vincent</creatorcontrib><creatorcontrib>RAMOT, Roee</creatorcontrib><creatorcontrib>BUNTIN, Kathrin</creatorcontrib><title>ANTIBODY DRUG CONJUGATES AND METHODS FOR MAKING THEREOF</title><description>This application discloses microorganisms and methods of producing GNAQ/GNA11 inhibitors and methods of making antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The disclosure also relates to formulations comprising antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor and methods of treating or preventing cancer using the formulations.</description><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>TRAPPING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB39AvxdPJ3iVRwCQp1V3D29_MKdXcMcQ1WcPRzUfB1DfHwdwlWcPMPUvB19Pb0c1cI8XANcvV342FgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BJiZG5qaWBo5GxkQoAQDkBSe3</recordid><startdate>20240911</startdate><enddate>20240911</enddate><creator>D'ALESSIO, Joseph Anthony</creator><creator>IYER, Shwetha</creator><creator>MAUDENS, Pierre</creator><creator>HAINZL, Dominik</creator><creator>KHERA, Eshita</creator><creator>FESSLER, Boris</creator><creator>FAN, Liqiong</creator><creator>MANCHADO ROBLES, Eusebio</creator><creator>BLUEMMEL, Anne-Sophie</creator><creator>GABRIEL, Doris</creator><creator>YERRAMILLI-RAO, Padmaja</creator><creator>WUERSCH, Kuno</creator><creator>PISTORIUS, Dominik</creator><creator>HOFFMASTER, Keith</creator><creator>ROMANET, Vincent</creator><creator>RAMOT, Roee</creator><creator>BUNTIN, Kathrin</creator><scope>EVB</scope></search><sort><creationdate>20240911</creationdate><title>ANTIBODY DRUG CONJUGATES AND METHODS FOR MAKING THEREOF</title><author>D'ALESSIO, Joseph Anthony ; IYER, Shwetha ; MAUDENS, Pierre ; HAINZL, Dominik ; KHERA, Eshita ; FESSLER, Boris ; FAN, Liqiong ; MANCHADO ROBLES, Eusebio ; BLUEMMEL, Anne-Sophie ; GABRIEL, Doris ; YERRAMILLI-RAO, Padmaja ; WUERSCH, Kuno ; PISTORIUS, Dominik ; HOFFMASTER, Keith ; ROMANET, Vincent ; RAMOT, Roee ; BUNTIN, Kathrin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4427590A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2024</creationdate><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>PEST REPELLANTS OR ATTRACTANTS</topic><topic>PLANT GROWTH REGULATORS</topic><topic>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</topic><topic>TRAPPING</topic><toplevel>online_resources</toplevel><creatorcontrib>D'ALESSIO, Joseph Anthony</creatorcontrib><creatorcontrib>IYER, Shwetha</creatorcontrib><creatorcontrib>MAUDENS, Pierre</creatorcontrib><creatorcontrib>HAINZL, Dominik</creatorcontrib><creatorcontrib>KHERA, Eshita</creatorcontrib><creatorcontrib>FESSLER, Boris</creatorcontrib><creatorcontrib>FAN, Liqiong</creatorcontrib><creatorcontrib>MANCHADO ROBLES, Eusebio</creatorcontrib><creatorcontrib>BLUEMMEL, Anne-Sophie</creatorcontrib><creatorcontrib>GABRIEL, Doris</creatorcontrib><creatorcontrib>YERRAMILLI-RAO, Padmaja</creatorcontrib><creatorcontrib>WUERSCH, Kuno</creatorcontrib><creatorcontrib>PISTORIUS, Dominik</creatorcontrib><creatorcontrib>HOFFMASTER, Keith</creatorcontrib><creatorcontrib>ROMANET, Vincent</creatorcontrib><creatorcontrib>RAMOT, Roee</creatorcontrib><creatorcontrib>BUNTIN, Kathrin</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>D'ALESSIO, Joseph Anthony</au><au>IYER, Shwetha</au><au>MAUDENS, Pierre</au><au>HAINZL, Dominik</au><au>KHERA, Eshita</au><au>FESSLER, Boris</au><au>FAN, Liqiong</au><au>MANCHADO ROBLES, Eusebio</au><au>BLUEMMEL, Anne-Sophie</au><au>GABRIEL, Doris</au><au>YERRAMILLI-RAO, Padmaja</au><au>WUERSCH, Kuno</au><au>PISTORIUS, Dominik</au><au>HOFFMASTER, Keith</au><au>ROMANET, Vincent</au><au>RAMOT, Roee</au><au>BUNTIN, Kathrin</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIBODY DRUG CONJUGATES AND METHODS FOR MAKING THEREOF</title><date>2024-09-11</date><risdate>2024</risdate><abstract>This application discloses microorganisms and methods of producing GNAQ/GNA11 inhibitors and methods of making antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The disclosure also relates to formulations comprising antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor and methods of treating or preventing cancer using the formulations.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP4427590A2
source esp@cenet
subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title ANTIBODY DRUG CONJUGATES AND METHODS FOR MAKING THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T16%3A56%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=D'ALESSIO,%20Joseph%20Anthony&rft.date=2024-09-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4427590A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true