2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS

Disclosed herein are 2-amino imidazole derivatives. These compounds inhibit Protein Arginine N-Methyl Transferase 5 (PRMT5) activity. In addition to the compounds, disclosed herein are pharmaceutical compositions containing the compounds, and methods of use, such as methods of treating cancer using...

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Bibliographische Detailangaben

Hauptverfasser:	LAWSON, John David, KULYK, Svitlana, SMITH, Christopher Ronald, IVETAC, Anthony
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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