GLIOBLASTOMA MULTIFORME TREATMENTS

HDAC-7 inhibitors and uses thereof are provided, including their uses as therapeutic agents for treating brain cancer and/or solid tumors, for example, glioblastoma multiforme (GBM). In some embodiments, provided herein are HDAC-7 inhibitors selected from small molecules, siRNAs, or HDAC class IIa i...

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Hauptverfasser: HASSAN, Ola, TAPINOS, Nikolaos, KARAMBIZI, David
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creator HASSAN, Ola
TAPINOS, Nikolaos
KARAMBIZI, David
description HDAC-7 inhibitors and uses thereof are provided, including their uses as therapeutic agents for treating brain cancer and/or solid tumors, for example, glioblastoma multiforme (GBM). In some embodiments, provided herein are HDAC-7 inhibitors selected from small molecules, siRNAs, or HDAC class IIa inhibitors, such as TMP269, or pharmaceutically acceptable salts thereof.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title GLIOBLASTOMA MULTIFORME TREATMENTS
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