GLIOBLASTOMA MULTIFORME TREATMENTS

HDAC-7 inhibitors and uses thereof are provided, including their uses as therapeutic agents for treating brain cancer and/or solid tumors, for example, glioblastoma multiforme (GBM). In some embodiments, provided herein are HDAC-7 inhibitors selected from small molecules, siRNAs, or HDAC class IIa i...

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Hauptverfasser:	HASSAN, Ola, TAPINOS, Nikolaos, KARAMBIZI, David
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	HDAC-7 inhibitors and uses thereof are provided, including their uses as therapeutic agents for treating brain cancer and/or solid tumors, for example, glioblastoma multiforme (GBM). In some embodiments, provided herein are HDAC-7 inhibitors selected from small molecules, siRNAs, or HDAC class IIa inhibitors, such as TMP269, or pharmaceutically acceptable salts thereof.