COMPOSITIONS AND METHODS FOR ENHANCING AND EXPANDING INFECTION INDUCED IMMUNITY

Methods and compositions are provided for the treatment of virus infections in a subject which can be a human subject. The methods include administering one or more doses of a composition comprising therapeutic double-stranded RNA (tdsRNA) to a subject after active viral replication in the nasal pas...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: STRAYER, David, R, EQUELS, Thomas, K
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Methods and compositions are provided for the treatment of virus infections in a subject which can be a human subject. The methods include administering one or more doses of a composition comprising therapeutic double-stranded RNA (tdsRNA) to a subject after active viral replication in the nasal passages of the subject. Following administration, the tdsRNA induces an enhanced and cross protective immune response to the virus or a broad-based immune response to the virus and variants thereof.