COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF ANGIOPOIETIN-LIKE 3 (ANGPTL3) PROTEIN

Compositions and methods useful to reduce expression of Angiopoietin-like 3 (ANGPTL3) gene and for treatment of ANGPTL3-associated diseases and conditions are provided. Provided are ANGPTL3 dsRNA agents, ANGPTL3 antisense polynucleotide agents, compositions comprising ANGPTL3 dsRNA agents, and, comp...

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Bibliographische Detailangaben
Hauptverfasser:	SHAO, Pengcheng Patrick, SHU, Dongxu
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Compositions and methods useful to reduce expression of Angiopoietin-like 3 (ANGPTL3) gene and for treatment of ANGPTL3-associated diseases and conditions are provided. Provided are ANGPTL3 dsRNA agents, ANGPTL3 antisense polynucleotide agents, compositions comprising ANGPTL3 dsRNA agents, and, compositions comprising ANGPTL3 antisense polynucleotide agents that can be used to reduce ANGPTL3 expression in cells and subjects.