CELLULAR MATRIX NERVE GRAFT FOR REPAIRING PERIPHERAL NERVE INJURY AND PREPARATION METHOD THEREFOR
The invention discloses a cell matrix nerve graft for repairing peripheral nerve injury and a preparation method thereof. The cell matrix nerve graft comprises acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization after secretion and formation of stem cells,...
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| creator | XU, Lingchi WANG, Shanshan QIAN, Tianmei XU, Lai LI, Meiyuan GONG, Leilei GU, Xiaosong SUN, Hualin WANG, Hongkui |
| description | The invention discloses a cell matrix nerve graft for repairing peripheral nerve injury and a preparation method thereof. The cell matrix nerve graft comprises acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization after secretion and formation of stem cells, and the acellular matrix is wrapped around the scaffold. The defects of autologous nerve transplantation repair can be overcome and the immunogenicity of allogeneic cell transplantation repair is avoided. The cell matrix nerve graft beneficial to nerve cell proliferation and migration is provided, a microenvironment beneficial to axon growth is established, the purposes of nerve regeneration and function repair are achieved, and a feasible solution is provided for clinical treatment of nerve defects. |
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The cell matrix nerve graft comprises acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization after secretion and formation of stem cells, and the acellular matrix is wrapped around the scaffold. The defects of autologous nerve transplantation repair can be overcome and the immunogenicity of allogeneic cell transplantation repair is avoided. 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The cell matrix nerve graft comprises acellular matrix and a scaffold, wherein the acellular matrix is obtained by decellularization after secretion and formation of stem cells, and the acellular matrix is wrapped around the scaffold. The defects of autologous nerve transplantation repair can be overcome and the immunogenicity of allogeneic cell transplantation repair is avoided. The cell matrix nerve graft beneficial to nerve cell proliferation and migration is provided, a microenvironment beneficial to axon growth is established, the purposes of nerve regeneration and function repair are achieved, and a feasible solution is provided for clinical treatment of nerve defects.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL |
| title | CELLULAR MATRIX NERVE GRAFT FOR REPAIRING PERIPHERAL NERVE INJURY AND PREPARATION METHOD THEREFOR |
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