ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES

The present disclosure provides a class of compounds including a ligand moiety that specifically binds to a cell surface asialoglycoprotein receptor (ASGPR). The cell surface ASGPR binding compounds can trigger the receptor to internalize into the cell a bound compound. The ligand moieties of this d...

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Bibliographische Detailangaben
Hauptverfasser: BUSCH, Brett, Bradley, TURTLE, Eric, D, ERNST, Justin, Thomas, LEWIS, Jason, G, PACKARD, Garrick, K
Format: Patent
Sprache:eng ; fre ; ger
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