ANTI-TM4SF4 HUMANIZED ANTIBODY AND USE THEREOF

The present invention relates to an anti-TM4SF4(TransMembrane 4 Superfamily Member 4) humanized antibody and use thereof. The anti-TM4SF4 humanized antibody of present invention has high affinity for binding specifically to TM4SF4 while exhibiting low immunogenicity in humans, and thus can be advant...

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Hauptverfasser: SHIN, Byung Chul, CHOI, Mun Ju, JUNG, U Hee, KAHM, Yeon Jee, KIM, In Gyu, KIM, Rae Kwon, RYU, Chun Jeih, KIM, Min Kyu, PARK, Hwangseo
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creator SHIN, Byung Chul
CHOI, Mun Ju
JUNG, U Hee
KAHM, Yeon Jee
KIM, In Gyu
KIM, Rae Kwon
RYU, Chun Jeih
KIM, Min Kyu
PARK, Hwangseo
description The present invention relates to an anti-TM4SF4(TransMembrane 4 Superfamily Member 4) humanized antibody and use thereof. The anti-TM4SF4 humanized antibody of present invention has high affinity for binding specifically to TM4SF4 while exhibiting low immunogenicity in humans, and thus can be advantageously used to detect TM4SF4 or to target cancer cells and cancer stem cells that overexpress TM4SF4.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
title ANTI-TM4SF4 HUMANIZED ANTIBODY AND USE THEREOF
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