SUBSTITUTED TETRAHYDROFURAN ANALOGS AS MODULATORS OF SODIUM CHANNELS
Compounds of formula I, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable sal...
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| creator | SKERRATT, Sarah CARVALHO MEIRELES, Lidio Marx SHAW, David Matthew PONTILLO, Joseph FRAYSSE, Damien GALAN, Bhairavi MUI, James Jun Bon STAMOS, Dean CHUDYK, Ewa Iwona GEDDIS, Stephen Michael PULLIN, Robert KNEGTEL, Ronald Marcellus SCHMIDT, Yvonne AUSTIN, James Robert JACQUES, Reece NORTH, Kiri ETXEBARRIA JARDI, Gorka HURLEY, Dennis James HADIDA RUAH, Sara S NEUBERT, Timothy Donald BECK, Elizabeth Mary STORCK, Pierre-Henri THOMSON, Stephen Andrew VIRANI, Anisa Nizarali AHMAD, Nadia M KINTZER, Alexander DURRANT, Steven John PINDER, Joanne Louise WRAY, Christopher SOUSA, Bruno Artur |
| description | Compounds of formula I, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain. |
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Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SUBSTITUTED TETRAHYDROFURAN ANALOGS AS MODULATORS OF SODIUM CHANNELS |
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