SPACIO-TEMPORAL DETERMINATION OF POLYPEPTIDE STRUCTURE

SPACIO-TEMPORAL DETERMINATION OF POLYPEPTIDE STRUCTURE

Disclosed herein are methods of in silico generation of polypeptide structures using time-based data generated from molecular dynamics simulations. Also disclosed herein are methods of predicting an epitope or binding surface of a polypeptide using in silico methods. Also disclosed herein are compos...

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Hauptverfasser: DUTTON, Oliver, FISICARO, Carlo, HEBERLING, Matthew Michael, HENDERSON, Louie Derek, TAMIOLA, Kamil, REDL, Istvan
Format: Patent
Sprache:eng ; fre ; ger
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INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
PHYSICS
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creator DUTTON, Oliver
FISICARO, Carlo
HEBERLING, Matthew Michael
HENDERSON, Louie Derek
TAMIOLA, Kamil
REDL, Istvan
description Disclosed herein are methods of in silico generation of polypeptide structures using time-based data generated from molecular dynamics simulations. Also disclosed herein are methods of predicting an epitope or binding surface of a polypeptide using in silico methods. Also disclosed herein are compositions containing polypeptide therapeutics designed to bind to a predicted epitope structure of a polypeptide, as well as methods of treating a subject by administering to the subject compositions containing the same.
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subjects INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
PHYSICS
title SPACIO-TEMPORAL DETERMINATION OF POLYPEPTIDE STRUCTURE
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