LIPIDIC NANOPARTICLES FOR MRNA DELIVERY

Disclosed herein are compositions for modulating the production of a protein in a target cell, in particular for ameliorating diseases associated with protein or enzyme deficiencies. The compositions comprise at least one mRNA encoding a polypeptide of interest, and a transfer vehicle comprising a l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DEROSA, Frank, GUILD, Braydon Charles, HEARTLEIN, Michael
Format: Patent
Sprache:eng ; fre ; ger
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