APPLICATION OF COMPOSITION IN PREPARATION OF DRUG FOR DIAGNOSING INFANTILE HEMANGIOMA AND/OR MONITORING PROGRESS AND PROGNOSIS THEREOF, AND KIT AND DRUG

An application of a composition in preparation of a drug for diagnosing infantile hemangioma (IH) and/or monitoring progress and prognosis thereof, and a test kit comprising the composition and instructions. The composition comprises at least one of the following four groups of substances: (1) at le...

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Bibliographische Detailangaben
1. Verfasser: Jiang, Chenghong
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An application of a composition in preparation of a drug for diagnosing infantile hemangioma (IH) and/or monitoring progress and prognosis thereof, and a test kit comprising the composition and instructions. The composition comprises at least one of the following four groups of substances: (1) at least one of a total fatty acid or a total saturated fatty acid or a total mono-unsaturated fatty acid or a specific fatty acid; (2) at least one of specific metabolites; (3) at least one of specific proteins; and (4) at least one of specific lipid subclass substances or lipid molecules. The application and the kit can realize early warning/prediction and early diagnosis of the IH, close monitoring of disease progress, objective evaluation of a treatment effect of the drug, and accurate reflection of prognosis. A drug for treating the IH comprises a substance regulating expression selected from the group consisting of LDHB, KRT1, BCHE, CFHR4, CPQ, APOC-3, ARHGDIB, and LAMAS, thereby providing a new effective way for treatment of the IH.