HALF-LIFE EXTENDING MOIETIES AND METHODS OF USING THE SAME

The disclosure relates generally to biology and medicine, and more particularly it relates to compounds acting as half-life (t½)-extending moieties for use with therapeutics, especially for improving t½ of biological-based therapeutics (i.e., biotherapeutics or biologics). The disclosure further rel...

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Hauptverfasser: HEUER, Josef George, LEE, Stacey Lynn, VERDINO, Petra, FERRANTE, Andrea
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creator HEUER, Josef George
LEE, Stacey Lynn
VERDINO, Petra
FERRANTE, Andrea
description The disclosure relates generally to biology and medicine, and more particularly it relates to compounds acting as half-life (t½)-extending moieties for use with therapeutics, especially for improving t½ of biological-based therapeutics (i.e., biotherapeutics or biologics). The disclosure further relates to fusions and conjugates that include one or more of the compounds acting as t½-extending moieties, as well as pharmaceutical compositions including the same and their use in treating various conditions, diseases or disorders.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title HALF-LIFE EXTENDING MOIETIES AND METHODS OF USING THE SAME
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