DESIGNED ANKYRIN REPEAT DOMAINS WITH BINDING SPECIFICITY FOR SERUM ALBUMIN

DESIGNED ANKYRIN REPEAT DOMAINS WITH BINDING SPECIFICITY FOR SERUM ALBUMIN

New designed ankyrin repeat domains with binding specificity for serum albumin, recombinant binding proteins comprising at least two designed ankyrin repeat domains with binding specificity for serum albumin, as well as recombinant binding proteins comprising at least one designed ankyrin repeat dom...

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Bibliographische Detailangaben
Hauptverfasser: MERZ, Frieder W, GULOTTI-GEORGIEVA, Maya, SONDEREGGER, Ivo, STUMPP, Michael T, PHILLIPS, Douglas, FORRER, Patrik, DOLADO, Ignacio, ABRAM SALIBA, Johan, BAKKER, Talitha, BINZ, Hans Kaspar, STEINER, Daniel
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:New designed ankyrin repeat domains with binding specificity for serum albumin, recombinant binding proteins comprising at least two designed ankyrin repeat domains with binding specificity for serum albumin, as well as recombinant binding proteins comprising at least one designed ankyrin repeat domain with binding specificity for hepatocyte growth factor (HGF), at least one designed ankyrin repeat domain with binding specificity for vascular endothelial growth factor (VEGF-A), and at least two designed ankyrin repeat domain with binding specificity for serum albumin are described, as well as nucleic acids encoding such designed ankyrin repeat domains and recombinant binding proteins, pharmaceutical compositions comprising such designed ankyrin repeat domains, recombinant binding proteins or nucleic acids and the use of such designed ankyrin repeat domains, recombinant binding proteins, nucleic acids or pharmaceutical compositions in the treatment of diseases.