NANOPATTERNED FILMS WITH PATTERNED SURFACE CHEMISTRY

An article includes a flexible structured film with a first major surface and a second major surface, wherein a first major surface of the flexible structured film has a plurality of posts separated by land areas, and the posts have an exposed surface. An anti-biofouling layer resides in the land ar...

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Hauptverfasser: FISHMAN, Joshua M, NICCUM, Kayla C, SOLOMON, Jeffrey L, ARMSTRONG, Paul B, BONILLA, Tonya D, TARNOWSKI, David J, NELSON, Caleb T, VAN LENGERICH, Henrik B, HUSTAD, Phillip D
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creator FISHMAN, Joshua M
NICCUM, Kayla C
SOLOMON, Jeffrey L
ARMSTRONG, Paul B
BONILLA, Tonya D
TARNOWSKI, David J
NELSON, Caleb T
VAN LENGERICH, Henrik B
HUSTAD, Phillip D
description An article includes a flexible structured film with a first major surface and a second major surface, wherein a first major surface of the flexible structured film has a plurality of posts separated by land areas, and the posts have an exposed surface. An anti-biofouling layer resides in the land areas, and the anti-biofouling layer has a methylated surface. An inorganic layer is on the exposed surfaces of the posts, wherein the inorganic layer includes a metal or a metal oxide. An analyte binding layer is on the inorganic layer, wherein the analyte binding layer is chosen from a reactive silane, a functionalizable hydrogel, a functionalizable polymer, and mixtures and combinations thereof. An exposed surface of the analyte binding layer includes at least one functional group selected to bind with a biochemical analyte.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title NANOPATTERNED FILMS WITH PATTERNED SURFACE CHEMISTRY
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