GLYCOSIDE DUAL-CLEAVAGE LINKERS FOR ANTIBODY-DRUG CONJUGATES

The present disclosure provides antibody-drug conjugate structures, which include a cleavable linker that links the antibody to the drug and has a first enzymatically cleavable moiety and a second enzymatically cleavable moiety which includes a glycoside selected from a galactoside, a glucoside, a m...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	CHUPRAKOV, Stepan, OGUNKOYA, Ayodele O
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES SUGARS
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