PLASMA KALLIKREIN INHIBITORS
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary ang...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | CERNAKA, Natalija JABRI, Salman TIAN, Maoqun OGAWA, Anthony Ken OSLER, Skylar, K SINZ, Christopher, J GAO, Ying-Duo SHARP, Phillip Patrick BAO, Jianming TANG, Haiqun LOPEZ, Jovan Alexander XIAO, Dong CHENG, Alan, C YANG, Song MERCHANT, Rohan |
| description | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4247372A4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4247372A4</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4247372A43</originalsourceid><addsrcrecordid>eNrjZJAJ8HEM9nVU8Hb08fH0DnL19FPw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BJkYm5sbmRo4mxkQoAQA85CCK</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PLASMA KALLIKREIN INHIBITORS</title><source>esp@cenet</source><creator>CERNAKA, Natalija ; JABRI, Salman ; TIAN, Maoqun ; OGAWA, Anthony Ken ; OSLER, Skylar, K ; SINZ, Christopher, J ; GAO, Ying-Duo ; SHARP, Phillip Patrick ; BAO, Jianming ; TANG, Haiqun ; LOPEZ, Jovan Alexander ; XIAO, Dong ; CHENG, Alan, C ; YANG, Song ; MERCHANT, Rohan</creator><creatorcontrib>CERNAKA, Natalija ; JABRI, Salman ; TIAN, Maoqun ; OGAWA, Anthony Ken ; OSLER, Skylar, K ; SINZ, Christopher, J ; GAO, Ying-Duo ; SHARP, Phillip Patrick ; BAO, Jianming ; TANG, Haiqun ; LOPEZ, Jovan Alexander ; XIAO, Dong ; CHENG, Alan, C ; YANG, Song ; MERCHANT, Rohan</creatorcontrib><description>The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241106&DB=EPODOC&CC=EP&NR=4247372A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241106&DB=EPODOC&CC=EP&NR=4247372A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CERNAKA, Natalija</creatorcontrib><creatorcontrib>JABRI, Salman</creatorcontrib><creatorcontrib>TIAN, Maoqun</creatorcontrib><creatorcontrib>OGAWA, Anthony Ken</creatorcontrib><creatorcontrib>OSLER, Skylar, K</creatorcontrib><creatorcontrib>SINZ, Christopher, J</creatorcontrib><creatorcontrib>GAO, Ying-Duo</creatorcontrib><creatorcontrib>SHARP, Phillip Patrick</creatorcontrib><creatorcontrib>BAO, Jianming</creatorcontrib><creatorcontrib>TANG, Haiqun</creatorcontrib><creatorcontrib>LOPEZ, Jovan Alexander</creatorcontrib><creatorcontrib>XIAO, Dong</creatorcontrib><creatorcontrib>CHENG, Alan, C</creatorcontrib><creatorcontrib>YANG, Song</creatorcontrib><creatorcontrib>MERCHANT, Rohan</creatorcontrib><title>PLASMA KALLIKREIN INHIBITORS</title><description>The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJAJ8HEM9nVU8Hb08fH0DnL19FPw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BJkYm5sbmRo4mxkQoAQA85CCK</recordid><startdate>20241106</startdate><enddate>20241106</enddate><creator>CERNAKA, Natalija</creator><creator>JABRI, Salman</creator><creator>TIAN, Maoqun</creator><creator>OGAWA, Anthony Ken</creator><creator>OSLER, Skylar, K</creator><creator>SINZ, Christopher, J</creator><creator>GAO, Ying-Duo</creator><creator>SHARP, Phillip Patrick</creator><creator>BAO, Jianming</creator><creator>TANG, Haiqun</creator><creator>LOPEZ, Jovan Alexander</creator><creator>XIAO, Dong</creator><creator>CHENG, Alan, C</creator><creator>YANG, Song</creator><creator>MERCHANT, Rohan</creator><scope>EVB</scope></search><sort><creationdate>20241106</creationdate><title>PLASMA KALLIKREIN INHIBITORS</title><author>CERNAKA, Natalija ; JABRI, Salman ; TIAN, Maoqun ; OGAWA, Anthony Ken ; OSLER, Skylar, K ; SINZ, Christopher, J ; GAO, Ying-Duo ; SHARP, Phillip Patrick ; BAO, Jianming ; TANG, Haiqun ; LOPEZ, Jovan Alexander ; XIAO, Dong ; CHENG, Alan, C ; YANG, Song ; MERCHANT, Rohan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4247372A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CERNAKA, Natalija</creatorcontrib><creatorcontrib>JABRI, Salman</creatorcontrib><creatorcontrib>TIAN, Maoqun</creatorcontrib><creatorcontrib>OGAWA, Anthony Ken</creatorcontrib><creatorcontrib>OSLER, Skylar, K</creatorcontrib><creatorcontrib>SINZ, Christopher, J</creatorcontrib><creatorcontrib>GAO, Ying-Duo</creatorcontrib><creatorcontrib>SHARP, Phillip Patrick</creatorcontrib><creatorcontrib>BAO, Jianming</creatorcontrib><creatorcontrib>TANG, Haiqun</creatorcontrib><creatorcontrib>LOPEZ, Jovan Alexander</creatorcontrib><creatorcontrib>XIAO, Dong</creatorcontrib><creatorcontrib>CHENG, Alan, C</creatorcontrib><creatorcontrib>YANG, Song</creatorcontrib><creatorcontrib>MERCHANT, Rohan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CERNAKA, Natalija</au><au>JABRI, Salman</au><au>TIAN, Maoqun</au><au>OGAWA, Anthony Ken</au><au>OSLER, Skylar, K</au><au>SINZ, Christopher, J</au><au>GAO, Ying-Duo</au><au>SHARP, Phillip Patrick</au><au>BAO, Jianming</au><au>TANG, Haiqun</au><au>LOPEZ, Jovan Alexander</au><au>XIAO, Dong</au><au>CHENG, Alan, C</au><au>YANG, Song</au><au>MERCHANT, Rohan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PLASMA KALLIKREIN INHIBITORS</title><date>2024-11-06</date><risdate>2024</risdate><abstract>The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP4247372A4 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PLASMA KALLIKREIN INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T23%3A49%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CERNAKA,%20Natalija&rft.date=2024-11-06&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4247372A4%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |