EXPRESSION SYSTEM FOR THE TREATMENT OF CANCER

EXPRESSION SYSTEM FOR THE TREATMENT OF CANCER

The invention relates to a recombinant expression system for the treatment of cancer based on the "Stimulator of interferon genes" (STING) and comprising two nucleic acid constructs. The invention further relates to an expression vector or a combination of two expression vectors encoding s...

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Hauptverfasser: PRIETO VALTUEÑA, Jesus M, GOULD, David James, HONORATO CÍA, Beatriz, MARCO MARTÍNEZ, Sonia, TENESACA CAYAMBE, Shirley Mireya
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator PRIETO VALTUEÑA, Jesus M
GOULD, David James
HONORATO CÍA, Beatriz
MARCO MARTÍNEZ, Sonia
TENESACA CAYAMBE, Shirley Mireya
description The invention relates to a recombinant expression system for the treatment of cancer based on the "Stimulator of interferon genes" (STING) and comprising two nucleic acid constructs. The invention further relates to an expression vector or a combination of two expression vectors encoding said nucleic acid construct(s) and to a viral particle or a combination of two viral particles comprising said expression vector(s). The invention also relates to a pharmaceutical composition that comprises said recombinant expression system, said expression vector(s) or said viral particle(s). The invention finally relates to the use of said recombinant expression system, said expression vector(s), said viral particle(s) or said pharmaceutical composition for use in an immunotherapy, especially in the immunotherapy of a proliferative disorder like cancer.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title EXPRESSION SYSTEM FOR THE TREATMENT OF CANCER
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