COVALENT CONJUGATES OF THE SARS-COV-2 RECEPTOR-BINDING DOMAIN AND A CARRIER PROTEIN AND VACCINE COMPOSITIONS THAT CONTAIN THEM

COVALENT CONJUGATES OF THE SARS-COV-2 RECEPTOR-BINDING DOMAIN AND A CARRIER PROTEIN AND VACCINE COMPOSITIONS THAT CONTAIN THEM

This invention pertains to biotechnology, more specifically to the field of human health. This document describes in particular conjugates of the SARS-CoV-2 receptor binding domain covalently conjugated to a carrier protein, the method used to obtain them, and the vaccine compositions that contain t...

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Hauptverfasser: GARCÍA RIVERA, Dagmar, OJITO MAGAZ, Eduardo, SÁNCHEZ RAMÍREZ, Belinda, RAMÍREZ GONZÁLEZ, Ubel Jesús, BOGGIANO AYO, Tammy, OLIVA HERNÁNDEZ, Reynaldo, SANTANA MEDEROS, Darielys, FERNÁNDEZ CASTILLO, Sonsire, VEREZ BENCOMO, Vicente Guillermo, GARCÍA RIVERA, Daniel, RODRÍGUEZ NODA, Laura Marta, VALDÉS BALBÍN, Yury, GARCÍA RICARDO, Manuel
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:This invention pertains to biotechnology, more specifically to the field of human health. This document describes in particular conjugates of the SARS-CoV-2 receptor binding domain covalently conjugated to a carrier protein, the method used to obtain them, and the vaccine compositions that contain them. The vaccine compositions described in this invention are useful for the prevention of the SARS-CoV-2 infection as they induce a strong response of neutralizing antibodies.