GENE THERAPY FOR OCULAR MANIFESTATIONS OF CLN2 DISEASE

Compositions and methods are described for the delivery of therapeutic products (such as therapeutic proteins (for example, antibodies), therapeutic RNAs (for example, shRNAs, siRNAs, and miRNAs), and therapeutic aptamers) to the retina/vitreal humour in the eyes of human subjects to treat pathologi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BUSS, Nicholas, Alexander Piers Sascha, KIM, Kwi, Hye, BAILEY, Alexander, Marston, PAKOLA, Stephen, Joseph, FALABELLA, Paulo, OHNSMAN, Christina, Maria, VAN EVEREN, Sherri
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator BUSS, Nicholas, Alexander Piers Sascha
KIM, Kwi, Hye
BAILEY, Alexander, Marston
PAKOLA, Stephen, Joseph
FALABELLA, Paulo
OHNSMAN, Christina, Maria
VAN EVEREN, Sherri
description Compositions and methods are described for the delivery of therapeutic products (such as therapeutic proteins (for example, antibodies), therapeutic RNAs (for example, shRNAs, siRNAs, and miRNAs), and therapeutic aptamers) to the retina/vitreal humour in the eyes of human subjects to treat pathologies of the eye, involving, for example, recombinant viral vectors such as recombinant adeno-associated virus (rAAV) vectors.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4225926A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4225926A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4225926A13</originalsourceid><addsrcrecordid>eNrjZDBzd_VzVQjxcA1yDIhUcPMPUvB3DvVxDFLwdfTzdHMNDnEM8fT3C1bwd1Nw9vEzUnDxDHZ1DHblYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgEmRkamlkZmjobGRCgBALBjJ1E</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>GENE THERAPY FOR OCULAR MANIFESTATIONS OF CLN2 DISEASE</title><source>esp@cenet</source><creator>BUSS, Nicholas, Alexander Piers Sascha ; KIM, Kwi, Hye ; BAILEY, Alexander, Marston ; PAKOLA, Stephen, Joseph ; FALABELLA, Paulo ; OHNSMAN, Christina, Maria ; VAN EVEREN, Sherri</creator><creatorcontrib>BUSS, Nicholas, Alexander Piers Sascha ; KIM, Kwi, Hye ; BAILEY, Alexander, Marston ; PAKOLA, Stephen, Joseph ; FALABELLA, Paulo ; OHNSMAN, Christina, Maria ; VAN EVEREN, Sherri</creatorcontrib><description>Compositions and methods are described for the delivery of therapeutic products (such as therapeutic proteins (for example, antibodies), therapeutic RNAs (for example, shRNAs, siRNAs, and miRNAs), and therapeutic aptamers) to the retina/vitreal humour in the eyes of human subjects to treat pathologies of the eye, involving, for example, recombinant viral vectors such as recombinant adeno-associated virus (rAAV) vectors.</description><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230816&amp;DB=EPODOC&amp;CC=EP&amp;NR=4225926A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230816&amp;DB=EPODOC&amp;CC=EP&amp;NR=4225926A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BUSS, Nicholas, Alexander Piers Sascha</creatorcontrib><creatorcontrib>KIM, Kwi, Hye</creatorcontrib><creatorcontrib>BAILEY, Alexander, Marston</creatorcontrib><creatorcontrib>PAKOLA, Stephen, Joseph</creatorcontrib><creatorcontrib>FALABELLA, Paulo</creatorcontrib><creatorcontrib>OHNSMAN, Christina, Maria</creatorcontrib><creatorcontrib>VAN EVEREN, Sherri</creatorcontrib><title>GENE THERAPY FOR OCULAR MANIFESTATIONS OF CLN2 DISEASE</title><description>Compositions and methods are described for the delivery of therapeutic products (such as therapeutic proteins (for example, antibodies), therapeutic RNAs (for example, shRNAs, siRNAs, and miRNAs), and therapeutic aptamers) to the retina/vitreal humour in the eyes of human subjects to treat pathologies of the eye, involving, for example, recombinant viral vectors such as recombinant adeno-associated virus (rAAV) vectors.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDBzd_VzVQjxcA1yDIhUcPMPUvB3DvVxDFLwdfTzdHMNDnEM8fT3C1bwd1Nw9vEzUnDxDHZ1DHblYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgEmRkamlkZmjobGRCgBALBjJ1E</recordid><startdate>20230816</startdate><enddate>20230816</enddate><creator>BUSS, Nicholas, Alexander Piers Sascha</creator><creator>KIM, Kwi, Hye</creator><creator>BAILEY, Alexander, Marston</creator><creator>PAKOLA, Stephen, Joseph</creator><creator>FALABELLA, Paulo</creator><creator>OHNSMAN, Christina, Maria</creator><creator>VAN EVEREN, Sherri</creator><scope>EVB</scope></search><sort><creationdate>20230816</creationdate><title>GENE THERAPY FOR OCULAR MANIFESTATIONS OF CLN2 DISEASE</title><author>BUSS, Nicholas, Alexander Piers Sascha ; KIM, Kwi, Hye ; BAILEY, Alexander, Marston ; PAKOLA, Stephen, Joseph ; FALABELLA, Paulo ; OHNSMAN, Christina, Maria ; VAN EVEREN, Sherri</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4225926A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>BUSS, Nicholas, Alexander Piers Sascha</creatorcontrib><creatorcontrib>KIM, Kwi, Hye</creatorcontrib><creatorcontrib>BAILEY, Alexander, Marston</creatorcontrib><creatorcontrib>PAKOLA, Stephen, Joseph</creatorcontrib><creatorcontrib>FALABELLA, Paulo</creatorcontrib><creatorcontrib>OHNSMAN, Christina, Maria</creatorcontrib><creatorcontrib>VAN EVEREN, Sherri</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BUSS, Nicholas, Alexander Piers Sascha</au><au>KIM, Kwi, Hye</au><au>BAILEY, Alexander, Marston</au><au>PAKOLA, Stephen, Joseph</au><au>FALABELLA, Paulo</au><au>OHNSMAN, Christina, Maria</au><au>VAN EVEREN, Sherri</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>GENE THERAPY FOR OCULAR MANIFESTATIONS OF CLN2 DISEASE</title><date>2023-08-16</date><risdate>2023</risdate><abstract>Compositions and methods are described for the delivery of therapeutic products (such as therapeutic proteins (for example, antibodies), therapeutic RNAs (for example, shRNAs, siRNAs, and miRNAs), and therapeutic aptamers) to the retina/vitreal humour in the eyes of human subjects to treat pathologies of the eye, involving, for example, recombinant viral vectors such as recombinant adeno-associated virus (rAAV) vectors.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP4225926A1
source esp@cenet
subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title GENE THERAPY FOR OCULAR MANIFESTATIONS OF CLN2 DISEASE
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T06%3A32%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BUSS,%20Nicholas,%20Alexander%20Piers%20Sascha&rft.date=2023-08-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4225926A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true