NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF

The present invention addresses the problem of providing a novel artificial nucleic acid, a method for producing the artificial nucleic acid, and a use of the artificial nucleic acid. The problem can be solved by an artificial nucleic acid having units derived from compound represented by formula (1...

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Bibliographische Detailangaben
Hauptverfasser:	IMANISHI, Takeshi, BAN, Ikuya, YOSHIKAWA, Haruhisa
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention addresses the problem of providing a novel artificial nucleic acid, a method for producing the artificial nucleic acid, and a use of the artificial nucleic acid. The problem can be solved by an artificial nucleic acid having units derived from compound represented by formula (1) or a salt thereof:[wherein: "Base" represents an aromatic heterocyclic group or an aromatic hydrocarbon ring group which may have a substituent; A1 represents a single bond or an alkylene group; R1 and R2 are the same as or different from each other and independently represent a hydrogen atom, an alkyl group, an alkenyl group, a cycloalkyl group, a cycloalkenyl group, or an aryl group which may have a substituent, a protecting group for a hydroxyl group, a phosphino group which has a substituent, or a dihydroxyphosphinyl group or a hydroxymercaptophosphinyl group which may have a substituent, or R1, R2, two oxygen atoms respectively adjacent to R1 and R2 and carbon atoms at position-3 to position-5 in a furanose together form a ring which may have a substituent; R3 represents a hydrogen atom, an alkyl group, an alkenyl group, a cycloalkyl group, an aryl group, or an acyl group which may have a substituent, a sulfonyl group or a silyl group which has a substituent, a functional molecule unit substituent, or a group represented by the formula: R31-X- (wherein R31 represents an amino group which may have a substituent; and X represents an alkylene group which may have a substituent, or a group having such a structure that at least one methylene group moiety in the alkylene group is substituted by -N(R32)- (wherein R32 represents a hydrogen atom or an alkyl group), -O- or -S(= O)k- (wherein k represents 0, 1 or 2)); R4 represents a hydrogen atom, an alkyl group or an aryl group which may have a substituent; R5 represents a hydrogen atom, an alkyl group or an aryl group which may have a substituent; R4 and R5 do not represent hydrogen atoms coincidentally; and n represents 0 or 1].