COMPOUNDS FOR THE REDUCING LIPOTOXIC DAMAGE

Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitor...

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Hauptverfasser: SINGH, Vijay P, ANANDAN, Sampath-Kumar, GREENMAN, Kevin, KAMAL, Zeeshan
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creator SINGH, Vijay P
ANANDAN, Sampath-Kumar
GREENMAN, Kevin
KAMAL, Zeeshan
description Provided herein are novel lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns, and acne. For example, provided herein are two novel lipase inhibitors useful in the methods described herein:or a pharmaceutically acceptable salt thereof.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOUNDS FOR THE REDUCING LIPOTOXIC DAMAGE
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