PLASMA KALLIKREIN INHIBITORS
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary ang...
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| creator | TIAN, Maoqun JABRI, Salman OGAWA, Anthony Ken HICKS, Jacqueline, D ZHAO, Zhiqiang SINZ, Christopher, J HAYES, Donna, A. A. W SHEARN-NANCE, Galen Paul BAO, Jianming KUANG, Rongze CHENG, Alan, C YANG, Song WU, Zhicai LANG, Simon, B |
| description | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein. |
| format | Patent |
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W ; SHEARN-NANCE, Galen Paul ; BAO, Jianming ; KUANG, Rongze ; CHENG, Alan, C ; YANG, Song ; WU, Zhicai ; LANG, Simon, B</creator><creatorcontrib>TIAN, Maoqun ; JABRI, Salman ; OGAWA, Anthony Ken ; HICKS, Jacqueline, D ; ZHAO, Zhiqiang ; SINZ, Christopher, J ; HAYES, Donna, A. A. W ; SHEARN-NANCE, Galen Paul ; BAO, Jianming ; KUANG, Rongze ; CHENG, Alan, C ; YANG, Song ; WU, Zhicai ; LANG, Simon, B</creatorcontrib><description>The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. 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W</au><au>SHEARN-NANCE, Galen Paul</au><au>BAO, Jianming</au><au>KUANG, Rongze</au><au>CHENG, Alan, C</au><au>YANG, Song</au><au>WU, Zhicai</au><au>LANG, Simon, B</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PLASMA KALLIKREIN INHIBITORS</title><date>2023-07-19</date><risdate>2023</risdate><abstract>The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | PLASMA KALLIKREIN INHIBITORS |
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