COMPOSITIONS OF SARS-COV-2 VACCINES BASED ON THE RECEPTOR BINDING DOMAIN, EXPRESSED AS A DIMER, AND THE OUTER MEMBRANE VESICLE OF MENINGOCOCCAL GROUP B BACTERIA

This invention is related to biotechnology; in particular, to the field of human health. The described vaccine compositions induce a neutralizing immune response against the SARS-CoV-2 virus. These compositions include a portion of the receptor binding protein of the SARS-Cov-2 virus, as antigen, ou...

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Hauptverfasser: CLIMENT RUIZ, Yanet, GARCÍA RIVERA, Dagmar, OJITO MAGAZ, Eduardo, SÁNCHEZ RAMÍREZ, Belinda, RAMÍREZ GONZÁLEZ, Ubel Jesús, BOGGIANO AYO, Tammy, OLIVA HERNÁNDEZ, Reynaldo, VEREZ BENCOMO, Vicente Guillermo, FERNÁNDEZ CASTILLO, Sonsire, PÉREZ NICADO, Rocmira, RODRÍGUEZ NODA, Laura Marta, CHEN, Guang Wu, VALDÉS BALBÍN, Yury, GONZÁLEZ RODRÍGUEZ, Humberto, CHOVEL CUERVO, Mario Landys
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:This invention is related to biotechnology; in particular, to the field of human health. The described vaccine compositions induce a neutralizing immune response against the SARS-CoV-2 virus. These compositions include a portion of the receptor binding protein of the SARS-Cov-2 virus, as antigen, outer-membrane vesicles of the Neisseria meningitides group B bacteria, as immunopotentiating component, and an adjuvant. The vaccine compositions that are described in this invention are useful in the prevention of infection with the SARS-CoV-2 virus.