GASTRO-RESISTANT HIGH-STRENGTH FORMULATION CONTAINING POSACONAZOLE

The present invention relates to a gastro-resistant high-strength unit dosage form comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains 300 mg posaconazole and an enteric polymer in a specific weight ratio. The unit dosage form may be a capsule or optionall...

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Hauptverfasser: PRATHAP, Vamshi Ramana, FITZNER, Ansgar, SCHLEHAHN, Hendrik, RALLABANDI, Bala Ramesha Chary, MUPKALKER, Ashwini Kumar, VELCHURI, Srikanth, KALAMATA, Venkatasimhadri Naidu, MADALLAPALLI, Kiran Kumar
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creator PRATHAP, Vamshi Ramana
FITZNER, Ansgar
SCHLEHAHN, Hendrik
RALLABANDI, Bala Ramesha Chary
MUPKALKER, Ashwini Kumar
VELCHURI, Srikanth
KALAMATA, Venkatasimhadri Naidu
MADALLAPALLI, Kiran Kumar
description The present invention relates to a gastro-resistant high-strength unit dosage form comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains 300 mg posaconazole and an enteric polymer in a specific weight ratio. The unit dosage form may be a capsule or optionally film-coated tablet.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title GASTRO-RESISTANT HIGH-STRENGTH FORMULATION CONTAINING POSACONAZOLE
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