SALTS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND SOLID FORMS OF SALTS, PHARMACEUTICAL COMPOSITION AND USE THEREOF

Provided are salts of a compound of formula (I) having an ATX inhibitory activity. The salts comprises inorganic acid salts or organic acid salts, and solid forms of the salts, such as crystal forms. The salts of the compound of formula (I) and their crystal forms according to the present disclosure...

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Hauptverfasser: YANG, Shaoxia, DING, Xiaohua, YANG, Qiongfeng, LIU, Min'an, LIU, Ming, LEI, Sijun, LI, Yuan, XIA, Qingfeng, LIU, Zhe, YUE, Yang, ZHANG, Shoubo, HU, Bin, ZHANG, Xuejun
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creator YANG, Shaoxia
DING, Xiaohua
YANG, Qiongfeng
LIU, Min'an
LIU, Ming
LEI, Sijun
LI, Yuan
XIA, Qingfeng
LIU, Zhe
YUE, Yang
ZHANG, Shoubo
HU, Bin
ZHANG, Xuejun
description Provided are salts of a compound of formula (I) having an ATX inhibitory activity. The salts comprises inorganic acid salts or organic acid salts, and solid forms of the salts, such as crystal forms. The salts of the compound of formula (I) and their crystal forms according to the present disclosure have a good solubility, stability and hygroscopicity, and are more suitable for medicinal use. Moreover, their preparation methods are simple and convenient, and are suitable for large-scale production.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SALTS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND SOLID FORMS OF SALTS, PHARMACEUTICAL COMPOSITION AND USE THEREOF
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