COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE

COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE

The present disclosure provides, for example, a composition comprising:2-(4-cyclopropyl-2-fluoroanilino)-3,4-difluoro-5-[[3-fluoro-2-(methylsu lfamoylamino)pyridin-4-yl]methyl]benzamide or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or salt;...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KANOH Takeo, NAKAE Shinichi
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator KANOH Takeo
NAKAE Shinichi
description The present disclosure provides, for example, a composition comprising:2-(4-cyclopropyl-2-fluoroanilino)-3,4-difluoro-5-[[3-fluoro-2-(methylsu lfamoylamino)pyridin-4-yl]methyl]benzamide or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or salt; and a dispersant (e.g., methylcellulose) and/or a basic compound (e.g., meglumine). According to the present disclosure, there is provided a composition comprising a specific aryl amide derivative that has RAF/MEK complex-stabilizing activity and/or MEK-inhibiting activity and is useful for the treatment or prevention of a cell proliferative disorder, particularly a cancer, the composition having good properties with respect to the dissolution and/or stability of the aryl amide derivative in the composition.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4186506A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4186506A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4186506A13</originalsourceid><addsrcrecordid>eNrjZNB29vcN8A_2DPH091Nw9vcLcfT08_RzV3AMivRx9PV0cVVwcQ3yDHMM8Qxz5WFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BJoYWZqYGZo6GxkQoAQBUYiTf</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE</title><source>esp@cenet</source><creator>KANOH Takeo ; NAKAE Shinichi</creator><creatorcontrib>KANOH Takeo ; NAKAE Shinichi</creatorcontrib><description>The present disclosure provides, for example, a composition comprising:2-(4-cyclopropyl-2-fluoroanilino)-3,4-difluoro-5-[[3-fluoro-2-(methylsu lfamoylamino)pyridin-4-yl]methyl]benzamide or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or salt; and a dispersant (e.g., methylcellulose) and/or a basic compound (e.g., meglumine). According to the present disclosure, there is provided a composition comprising a specific aryl amide derivative that has RAF/MEK complex-stabilizing activity and/or MEK-inhibiting activity and is useful for the treatment or prevention of a cell proliferative disorder, particularly a cancer, the composition having good properties with respect to the dissolution and/or stability of the aryl amide derivative in the composition.</description><language>eng ; fre ; ger</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230531&amp;DB=EPODOC&amp;CC=EP&amp;NR=4186506A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230531&amp;DB=EPODOC&amp;CC=EP&amp;NR=4186506A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KANOH Takeo</creatorcontrib><creatorcontrib>NAKAE Shinichi</creatorcontrib><title>COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE</title><description>The present disclosure provides, for example, a composition comprising:2-(4-cyclopropyl-2-fluoroanilino)-3,4-difluoro-5-[[3-fluoro-2-(methylsu lfamoylamino)pyridin-4-yl]methyl]benzamide or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or salt; and a dispersant (e.g., methylcellulose) and/or a basic compound (e.g., meglumine). According to the present disclosure, there is provided a composition comprising a specific aryl amide derivative that has RAF/MEK complex-stabilizing activity and/or MEK-inhibiting activity and is useful for the treatment or prevention of a cell proliferative disorder, particularly a cancer, the composition having good properties with respect to the dissolution and/or stability of the aryl amide derivative in the composition.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB29vcN8A_2DPH091Nw9vcLcfT08_RzV3AMivRx9PV0cVVwcQ3yDHMM8Qxz5WFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BJoYWZqYGZo6GxkQoAQBUYiTf</recordid><startdate>20230531</startdate><enddate>20230531</enddate><creator>KANOH Takeo</creator><creator>NAKAE Shinichi</creator><scope>EVB</scope></search><sort><creationdate>20230531</creationdate><title>COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE</title><author>KANOH Takeo ; NAKAE Shinichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4186506A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KANOH Takeo</creatorcontrib><creatorcontrib>NAKAE Shinichi</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KANOH Takeo</au><au>NAKAE Shinichi</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE</title><date>2023-05-31</date><risdate>2023</risdate><abstract>The present disclosure provides, for example, a composition comprising:2-(4-cyclopropyl-2-fluoroanilino)-3,4-difluoro-5-[[3-fluoro-2-(methylsu lfamoylamino)pyridin-4-yl]methyl]benzamide or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or salt; and a dispersant (e.g., methylcellulose) and/or a basic compound (e.g., meglumine). According to the present disclosure, there is provided a composition comprising a specific aryl amide derivative that has RAF/MEK complex-stabilizing activity and/or MEK-inhibiting activity and is useful for the treatment or prevention of a cell proliferative disorder, particularly a cancer, the composition having good properties with respect to the dissolution and/or stability of the aryl amide derivative in the composition.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP4186506A1
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOSITION CONTAINING ARYLAMIDE DERIVATIVE
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T15%3A06%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KANOH%20Takeo&rft.date=2023-05-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4186506A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true