PLASMA KALLIKREIN INHIBITORS

The present invention provides a compound of Formula Iand pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioe...

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Hauptverfasser: TIAN, Maoqun, HICKS, Jacqueline, D, ZHAO, Zhiqiang, SINZ, Christopher, J, SHARP, Phillip Patrick, SHEARN-NANCE, Galen Paul, LOMBARDO, Matthew, J, BAO, Jianming, KUANG, Rongze, LOPEZ, Jovan Alexander, CHENG, Alan, C, YANG, Song, WU, Zhicai, MERCHANT, Rohan
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creator TIAN, Maoqun
HICKS, Jacqueline, D
ZHAO, Zhiqiang
SINZ, Christopher, J
SHARP, Phillip Patrick
SHEARN-NANCE, Galen Paul
LOMBARDO, Matthew, J
BAO, Jianming
KUANG, Rongze
LOPEZ, Jovan Alexander
CHENG, Alan, C
YANG, Song
WU, Zhicai
MERCHANT, Rohan
description The present invention provides a compound of Formula Iand pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PLASMA KALLIKREIN INHIBITORS
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