PLASMA KALLIKREIN INHIBITORS
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary ang...
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| creator | JABRI, Salman TIAN, Maoqun HICKS, Jacqueline, D ZHAO, Zhiqiang SINZ, Christopher, J GAO, Ying-Duo SHEARN-NANCE, Galen, Paul LOMBARDO, Matthew, J OGAWA, Anthony, Ken BAO, Jianming KUANG, Rongze CHENG, Alan, C YANG, Song TAOKA, Brandon, M WU, Zhicai LANG, Simon, B HAYES, Donna, A., A., W |
| description | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein. |
| format | Patent |
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The compounds are selective inhibitors of plasma kallikrein.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PLASMA KALLIKREIN INHIBITORS |
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