METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS

A process is provided for making a WEE1 inhibitor of the formula (1A) useful in the treatment of conditions characterized by excessive cellular proliferation, such as cancer. In some embodiments, processes are provided for making intermediate compounds of the formulae (3), (5) and (6) as defined her...

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Hauptverfasser: ZHU, Shuguang, ABRAHAM, Sunny, BUNKER, Kevin, Duane, BOGA, Sobhana, Babu, WU, Tao, PRATT, Benjamin, HUANG, Peter, Qinhua, BOREN, Brant, Clayton, HOPKINS, Chad, Daniel
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creator ZHU, Shuguang
ABRAHAM, Sunny
BUNKER, Kevin, Duane
BOGA, Sobhana, Babu
WU, Tao
PRATT, Benjamin
HUANG, Peter, Qinhua
BOREN, Brant, Clayton
HOPKINS, Chad, Daniel
description A process is provided for making a WEE1 inhibitor of the formula (1A) useful in the treatment of conditions characterized by excessive cellular proliferation, such as cancer. In some embodiments, processes are provided for making intermediate compounds of the formulae (3), (5) and (6) as defined herein.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS
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