SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF

SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF

The present invention provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LI, Ting, CHE, Chao, XIANG, Dehu, XU, Zhengshuang, ZHANG, Qingzhou, CHEN, Huangcan, YANG, Zhen, ZHU, Zhendong, CHEN, Sigui
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator LI, Ting
CHE, Chao
XIANG, Dehu
XU, Zhengshuang
ZHANG, Qingzhou
CHEN, Huangcan
YANG, Zhen
ZHU, Zhendong
CHEN, Sigui
description The present invention provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBV infection in a lytic and/or latent phase.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4151621A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4151621A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4151621A13</originalsourceid><addsrcrecordid>eNqNiksKwjAQQLtxIeod5gB2EX_7aTttBtJMSSduS5G4Ei3U-6OiB3D1Ho-3zKa-RefyVhyV0RGwt1ywSgDF0JCyb4AKOHOIPfhYOsIA6JUb8tAFUWK_fQt1GFBZPLSkVipQS4Fq-cwVxJ6-Qep1triOtzltflxlUJOWNk_TY0jzNF7SPT0H6g7maE47g2b_x_ICg8g3fw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF</title><source>esp@cenet</source><creator>LI, Ting ; CHE, Chao ; XIANG, Dehu ; XU, Zhengshuang ; ZHANG, Qingzhou ; CHEN, Huangcan ; YANG, Zhen ; ZHU, Zhendong ; CHEN, Sigui</creator><creatorcontrib>LI, Ting ; CHE, Chao ; XIANG, Dehu ; XU, Zhengshuang ; ZHANG, Qingzhou ; CHEN, Huangcan ; YANG, Zhen ; ZHU, Zhendong ; CHEN, Sigui</creatorcontrib><description>The present invention provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBV infection in a lytic and/or latent phase.</description><language>eng ; fre ; ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230322&amp;DB=EPODOC&amp;CC=EP&amp;NR=4151621A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230322&amp;DB=EPODOC&amp;CC=EP&amp;NR=4151621A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI, Ting</creatorcontrib><creatorcontrib>CHE, Chao</creatorcontrib><creatorcontrib>XIANG, Dehu</creatorcontrib><creatorcontrib>XU, Zhengshuang</creatorcontrib><creatorcontrib>ZHANG, Qingzhou</creatorcontrib><creatorcontrib>CHEN, Huangcan</creatorcontrib><creatorcontrib>YANG, Zhen</creatorcontrib><creatorcontrib>ZHU, Zhendong</creatorcontrib><creatorcontrib>CHEN, Sigui</creatorcontrib><title>SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF</title><description>The present invention provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBV infection in a lytic and/or latent phase.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNiksKwjAQQLtxIeod5gB2EX_7aTttBtJMSSduS5G4Ei3U-6OiB3D1Ho-3zKa-RefyVhyV0RGwt1ywSgDF0JCyb4AKOHOIPfhYOsIA6JUb8tAFUWK_fQt1GFBZPLSkVipQS4Fq-cwVxJ6-Qep1triOtzltflxlUJOWNk_TY0jzNF7SPT0H6g7maE47g2b_x_ICg8g3fw</recordid><startdate>20230322</startdate><enddate>20230322</enddate><creator>LI, Ting</creator><creator>CHE, Chao</creator><creator>XIANG, Dehu</creator><creator>XU, Zhengshuang</creator><creator>ZHANG, Qingzhou</creator><creator>CHEN, Huangcan</creator><creator>YANG, Zhen</creator><creator>ZHU, Zhendong</creator><creator>CHEN, Sigui</creator><scope>EVB</scope></search><sort><creationdate>20230322</creationdate><title>SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF</title><author>LI, Ting ; CHE, Chao ; XIANG, Dehu ; XU, Zhengshuang ; ZHANG, Qingzhou ; CHEN, Huangcan ; YANG, Zhen ; ZHU, Zhendong ; CHEN, Sigui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4151621A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2023</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>LI, Ting</creatorcontrib><creatorcontrib>CHE, Chao</creatorcontrib><creatorcontrib>XIANG, Dehu</creatorcontrib><creatorcontrib>XU, Zhengshuang</creatorcontrib><creatorcontrib>ZHANG, Qingzhou</creatorcontrib><creatorcontrib>CHEN, Huangcan</creatorcontrib><creatorcontrib>YANG, Zhen</creatorcontrib><creatorcontrib>ZHU, Zhendong</creatorcontrib><creatorcontrib>CHEN, Sigui</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI, Ting</au><au>CHE, Chao</au><au>XIANG, Dehu</au><au>XU, Zhengshuang</au><au>ZHANG, Qingzhou</au><au>CHEN, Huangcan</au><au>YANG, Zhen</au><au>ZHU, Zhendong</au><au>CHEN, Sigui</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF</title><date>2023-03-22</date><risdate>2023</risdate><abstract>The present invention provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides a small-molecule inhibitor targeting an EB virus nuclear antigen protein, and/or a pharmaceutical composition containing the same, which can be used for the treatment of a disease caused by EBV infection in a lytic and/or latent phase.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP4151621A1
source esp@cenet
subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T17%3A57%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LI,%20Ting&rft.date=2023-03-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4151621A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true